血清C肽与糖化血红蛋白联合检验对糖尿病诊断的临床应用价值  

The Clinical Value of Combined Test of Serum C Peptide and Glycosylated Hemoglobin in the Diagnosis of Diabetes

作　　者：周冬梅[1] ZHOU Dong-mei(Department of Laboratory Medicine,Second People's Hospital of Jilin City,Jilin,Jilin Province,132002 China)

机构地区：[1]吉林省吉林市第二人民医院检验科,吉林吉林132002

出　　处：《糖尿病新世界》2020年第24期72-74,共3页Diabetes New World Magazine

摘　　要：目的探究血清C肽与糖化血红蛋白联合检验对糖尿病诊断的临床诊断价值。方法该次研究中的实验对象抽选2018年1月—2020年6月在该院接受诊治的糖尿病患者(46例)并选取同时期在该院体检的健康者(46名),将其分别划为研究组与健康组,两组受检者均接受血清C肽、糖化血红蛋白检验,观察并对比两组受检者空腹血糖、餐后2 h血糖、血清C肽以及糖化血红蛋白水平。结果研究组空腹血糖、餐后2 h血糖、餐前血清C肽、餐后血清C肽以及糖化血红蛋白分别为(8.95±1.31)mmol/L、(11.56±2.63)mmol/L、(1.14±0.51)μg/L、(4.91±1.09)μg/L、(9.69±1.51)%,均高于健康组各项数据,差异有统计学意义(t=17.858、11.682、3.731、13.455、17.405,P<0.05)。结论血清C肽与糖化血红蛋白联合检验在糖尿病临床诊断中具有显著的应用价值,能够明显区分糖尿病与健康者临床指标的差异性,可为临床治疗提供科学的参考依据。Objective To explore the clinical diagnostic value of the combined test of serum C-peptide and glycosylated hemoglobin in the diagnosis of diabetes.Methods The experimental subjects in this study selected diabetic patients(46 cases)who were diagnosed and treated in the hospital from January 2018 to June 2020,and selected healthy people(46 people)who received physical examination in our hospital during the same period.The subjects were divided into study group and healthy group.Both groups of subjects received serum C-peptide and glycosylated hemoglobin tests.The fasting blood glucose,2 h postprandial blood glucose,serum C-peptide and glycosylated hemoglobin levels were observed and compared between the two groups.Results The fasting blood glucose,2 h postprandial blood glucose,serum C-peptide,postprandial C-peptide and glycosylated hemoglobin of the study group were(8.95±1.31)mmol/L,(11.56±2.63)mmol/L,(1.14±0.51)μg/L,(4.91±1.09)μg/L,(9.69±1.51)%,all higher than the data of the healthy group,the difference was statistically significant(t=17.858,11.682,3.731,13.455,17.405,P<0.05).Conclusion The combined test of serum C-peptide and glycosylated hemoglobin has significant application value in the clinical diagnosis of diabetes.It can clearly distinguish the difference between the clinical indicators of diabetes and healthy people,and can provide scientific reference for clinical treatment.

关 键 词：糖尿病 临床诊断 空腹血糖 糖化血红蛋白 血清C肽 

分 类 号：R59[医药卫生—内科学]