单味中药提取物治疗非小细胞肺癌的研究进展  

Progress in research of single-flavor traditional Chinese medicine extracts in the treatment of non-small cell lung cancer

作　　者：李阳 张琨[1] 张泽良[1] 俞杞泉[1] 包祺[1] 吴春晓[1] 寿伟臻[1] LI Yang;ZHANG Kun;ZHANG Ze-liang;YU Qi-quan;BAO Qi;WU Chun-xiao;SHOU Wei-zhen(Longhua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China)

机构地区：[1]上海中医药大学附属龙华医院,上海200032

出　　处：《海南医学院学报》2021年第4期311-314,320,共5页Journal of Hainan Medical University

基　　金：上海市卫生和健康委优秀人才培养计划项目(1705)。

摘　　要：肺癌是目前发病率和死亡率较高的疾病之一,非小细胞肺癌又在其中占很大比例,中医药在治疗肿瘤方面具有悠久的历史,随着科技的进步,中药提取物越来越受到科研工作者的重视,目前多项研究证明如黄芪、片姜黄、人参、薏苡仁、鸦胆子等中药提取物能够抑制肿瘤细胞的增殖,且和放化疗等治疗手段联用时具有协同作用,其作用机制多和调节细胞周期、抑制癌症相关基因表达、诱导细胞凋亡等相关,相信随着提纯技术的发展,中药提取物会发挥更大的作用。Lung cancer is one of the diseases with high morbidity and mortality,and non-small cell lung cancer accounts for a large proportion of it.Traditional Chinese medicine has a long history in treating tumors.More and more researchers have paid more attention to it.At present,many studies have proved that traditional Chinese medicine extracts such as astragalus,turmeric,ginseng,coix seed,and gallbladder can inhibit tumor cell proliferation,and have synergistic effects when used in combination with radiotherapy and chemotherapy.Its mechanism of action is mostly related to regulating the cell cycle,inhibiting the expression of cancer-related genes,and inducing apoptosis.It is believed that with the development of purification technology,traditional Chinese medicine extracts will play a greater role.

关 键 词：非小细胞肺癌 单味中药 治疗 

分 类 号：R273[医药卫生—中西医结合]