火针联合其他疗法治疗结节性痒疹的Meta分析  

Meta Analysis on the Treatment of Prurigo Nodosa by Fire Acupuncture Combined with Other Therapies

作　　者：汤胜男 赵党生[1,2] 王凤仪 李洋洋[1] 刘志杰 曹思齐 TANG Shengnan;ZHAO Dangsheng;WANG Fengyi;LI Yangyang;LIU Zhijie;CAO Siqi(Gansu University of Chinese Medicine,Lanzhou 730300,China;Affiliated Hospital of Baoan Pure Traditional Chinese Medicine,Shenzhen 518000,China)

机构地区：[1]甘肃中医药大学,甘肃兰州730030 [2]宝安纯中医治疗医院,广东深圳518000

出　　处：《中国民族民间医药》2021年第2期67-71,共5页Chinese Journal of Ethnomedicine and Ethnopharmacy

摘　　要：目的:系统评价火针联合其他疗法治疗结节性痒疹的临床疗效和安全性。方法:使用计算机检索Pubmed、Cochran、CBM、CNKI、WanFang、VIP等数据库,检索时间为建库至2020年3月,由2名评价员对文献进行筛选、提取,采用Cochrane评价方法对文章的风险偏倚进行评价,并用RevMan 5.3软件进行Meta分析。结果:最终纳入11项RCT,868例患者。与对照组相比,火针联合其他疗法的临床总有效率相对较高[OR=3.60,95%CI(2.31~5.62),P<0.00001];治愈率也相对较高[OR=2.90,95%CI(2.16~3.89),P<0.00001];不良反应发生率低[OR=2.61,95%CI(0.88~7.75),P<0.00001];随访的复发率低有1项,无比较意义。结论:火针联合其他疗法相对于对照组治疗更具有临床疗效和安全性。但由于本研究数量有限及质量不佳,仍需大样本、高质量的文献进一步证实结果。Objective to systematically evaluate the clinical efficacy and safety of fire needle combined with other therapies in the treatment of prurigo nodularis.Methods Databases such as Pubmed,Cochrane Library,CBM,CNKI,WanFang and VIP were searched by computer.After two evaluators screened and extracted the literature,and used Cochrane evaluation method to evaluate the risk bias of the article,then they performed a Meta analysis using RevMan 5.3 software.And the retrieval time is from the establishment of the database to March 2020.Results 11 RCTs were finally included,with a total of 868 cases.Compared with the control group,the total clinical effective rate of fire acupuncture combined with other therapies is relatively high[OR=3.60,95%CI(2.31~5.62),P<0.00001];The cure rate is relatively high[OR=2.90,95%CI(2.16~3.89),P<0.00001];and the low incidence of adverse reactions[OR=2.61,95%CI(0.88~7.75),P<0.00001];The recurrence rate of follow-up was 1 item lower,which was of no significance.Conclusion Compared with the control group,fire acupuncture combined with other therapies has more clinical efficacy and safety.However,due to the limited quantity and poor quality of this study,it still needs large samples and high-quality literature to further confirm the results.

关 键 词：火针 结节性痒疹 META分析 

分 类 号：R758.69[医药卫生—皮肤病学与性病学]