不同蛋白饮食对肾病综合征患者的影响研究  

Effects of different protein diets on patients with nephrotic syndrome

作　　者：李娜[1] LI Na(VIP Internal Medical Department,The Fourth People's Hospital of Shenyang,Shenyang,Liaoning,110000,China)

机构地区：[1]沈阳市第四人民医院干诊内科,辽宁沈阳110000

出　　处：《中国冶金工业医学杂志》2021年第1期1-3,共3页Chinese Medical Journal of Metallurgical industry

基　　金：国家“十二五”科技支撑计划项目(2014BAI10B00)。

摘　　要：目的探讨不同蛋白质摄入量饮食对肾病综合征患者的影响。方法选取2018年10月~2019年10月我院收治的278例肾病综合征患者的临床资料,根据其每天蛋白摄入量的不同分为极低摄入量组(VLPD)53例、低摄入量组(LPD)78例、正常摄入量组(NPD)82例、高摄入量组(HPD)65例,比较4组患者的临床特点。结果不同蛋白摄入量组在血钙、ALB、24 h-Upro、GFR方面比较,差异均有统计学意义(均P<0.05)。NDP组血栓栓塞发生率低于VLDP组和LDP组,组间比较差异有统计学意义(P<0.05),其余组间比较差异无统计学意义(P>0.05)。结论不同蛋白质摄入量饮食对肾病综合征患者临床指标存在影响,是本病发生发展的相关因素。Objective To explore the effect of different protein diets on patients with nephrotic syndrome. Methods A total of 278 patients with nephrotic syndrome in our hospital from October 2018 to October 2019 were selected and divided into very low intake group(VLPD)(n=53), low intake group(LPD)(n=78), normal intake group(NPD)(n=82)and high intake group(HPD)(n=65). The clinical characteristics of patients in the four groups were compared. Results The differences of serum calcium, plasma albumin(ALB), 24 h urinary protein quantification(24 h-Upro), and glomerular filtration rate(GFR)between patients with nephrotic syndrome in different groups were statistically significant(all P<0.05). The incidence of thromboembolism in the NDP group was significantly lower than the VLDP group and the LDP group, the differences in the three groups were statistically significant(P<0.05). The differences among other groups were no statistically significant(P>0.05). Conclusion Diets with different protein intake has an impact on the clinical indicators of patients with nephrotic syndrome, which is the related factor of its occurrence and development of this disease.

关 键 词：肾病综合征 蛋白质摄入量 蛋白尿 肾小球滤过率 

分 类 号：R692[医药卫生—泌尿科学]