绞股蓝维E口含片中皂苷A的含量测定研究  

Study on the Determination of Gypenoside A in Gynostava Pentaphylla Vitamin E Buccal Tablet

作　　者：梁香[1] 钟娜娜 蓝梓钰 吴凌凤[1] LIANG Xiang;ZHONG Nana;LAN Ziyu;WU Lingfeng(Medical College,Jiaying University,Meizhou 514031,China;不详)

机构地区：[1]嘉应学院医学院,广东梅州514031

出　　处：《中外医学研究》2021年第2期180-182,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

基　　金：嘉应学院医学院青年教师科研成长基金项目(2017A04);嘉应学院科技项目(2017KJY01);梅州市社会发展科技计划项目(2018B059)。

摘　　要：目的:建立绞股蓝维E口含片的质量控制方法,为其质量标准提供参考。方法:采用紫外分光光度法在全波长范围扫描,确定最大吸收波长为205 nm,在此波长测定绞股蓝维E口含片中绞股蓝皂苷A成分的含量。结果:绞股蓝皂苷A检测浓度在0.042 0~0.252 0 mg/ml范围内与吸光度之间具有良好的线性关系,每片绞股蓝维E口含片中绞股蓝皂苷A的含量约为0.617 mg。结论:本文建立的含量测定方法简便可行、准确、重复性好,适用于绞股蓝维生素E口含片的质量控制。Objective:To establish a quality control method for Gynostava Pentaphylla Vitamin E Buccal Tablet and provide reference for its quality standard.Method:Ultraviolet spectrophotometry was used to scan in the full wavelength range,and the maximum absorption wavelength was determined to be 205 nm.The content of Gypenoside A in Gynostava Pentaphylla Vitamin E Buccal Tablet was determined by this method.Result:There was a good linear relationship between Gypenoside A and absorbance in the range of 0.042 0-0.252 0 mg/ml,and the content of Gypenoside A in each Gynostava Pentaphylla Vitamin E Buccal Tablet was about 0.617 mg.Conclusion:The content determination method established in this paper is simple,feasible,accurate and reproducible.It is suitable for the quality control of Gynostava Pentaphylla Vitamin E Buccal Tablet.

关 键 词：绞股蓝维E口含片 绞股蓝皂苷A 紫外分光光度法 含量测定 

分 类 号：R286.0[医药卫生—中药学]