丙种球蛋白联合那屈肝素治疗对复发性流产患者保胎成功率的影响  

Effect of Gamma Globulin Combined with Nadroparin on the Success Rate of Miscarriage in Patients with Recurrent Spontaneous Abortion

作　　者：刘晓艳 LIU Xiaoyan(Huizhou Central Hospital,Huizhou 516008,China)

机构地区：[1]惠州市中心医院,广东惠州516008

出　　处：《中外医学研究》2021年第3期16-18,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨丙种球蛋白联合那屈肝素治疗对复发性流产患者保胎成功率的影响。方法:选取2018年1月-2019年12月在笔者所在医院治疗的复发性流产患者64例,按治疗不同分为两组,对照组采用常规保胎法治疗,研究组采用丙种球蛋白联合那屈肝素治疗。比较两组免疫功能、激素水平、保胎成功率。结果:研究组治疗后IgM、IgG、IgA水平均高于对照组,差异均有统计学意义(P<0.05);研究组治疗后E2、β-hCG、黄体酮水平均高于对照组,差异均有统计学意义(P<0.05);研究组保胎成功率高于对照组,差异有统计学意义(P<0.05)。结论:复发性流产患者使用丙种球蛋白联合那屈肝素治疗,患者免疫功能、激素水平有显著改善,保胎效果较好,具有良好的应用价值。Objective:To investigate the effect of Gamma Globulin combined with Nadroparin in treatment of recurrent abortion.Method:Sixty-four patients with recurrent miscarriage treated from January 2018 to December 2019 were selected and divided into two groups according to different treatments.The control group was treated with conventional fetal preservation,and the study group was treated with Gamma Globulin combined with Nadroparin.The immune function,hormone levels,and fetal success rate were compared between the two groups.Result:The levels of IgM,IgG and IgA in the study group were higher than those in the control group after treatment,the differences were statistically significant (P<0.05).The levels of E2,β-hCG and progesterone in the study group were higher than those in the control group after treatment,the differences were statistically significant (P<0.05).The success rate of fetal preservation in the study group was higher than that in the control group,the difference was statistically significant (P<0.05).Conclusion:Patients with recurrent abortion treated with Gamma Globulin combined with Nachroheparin can significantly improve their immune function and hormone levels,and the effect of fetal protection is good,which has good application value.

关 键 词：丙种球蛋白 那屈肝素 反复性流产 激素水平 免疫功能 

分 类 号：R714.21[医药卫生—妇产科学]