磁共振扩散加权成像对晚期卵巢癌患者腹膜癌指数预测的可行性研究  

The feasibility study of diffusion weighted magnetic resonance imaging in predicting peritoneal cancer index in patients with advanced ovarian cancer

作　　者：万载鑫 陆宇博 李丹 WAN Zaixin;LU Yubo;LI Dan(Department of Radiology,Dandong Hospital of Traditional Chinese Medicine,Dandong 118000,China;Department of Radiology,Panjin Central Hospital,Panjin 124000,China)

机构地区：[1]丹东市中医院放射科,丹东118000 [2]盘锦市中心医院放射科,盘锦124000

出　　处：《磁共振成像》2021年第2期83-85,共3页Chinese Journal of Magnetic Resonance Imaging

摘　　要：目的评估磁共振扩散加权成像(diffusion weighted imaging,DWI)预测晚期卵巢癌患者腹膜癌指数(peritoneal cancer index,PCI)的潜力,以及预测患者能否行完全肿瘤细胞减灭术。材料与方法回顾性研究2016年6月至2018年5月在丹东市中医院接受肿瘤细胞减灭术治疗的25例晚期卵巢癌(FIGO IIb期及以上)患者。纳入患者均于术前行1.5 T磁共振DWI扫描[DW-MRI检查中扫描序列有T1与T2加权成像序列、对比增强T1加权与DWI(b=0、1000 s/mm^2)序列]。由两位放射学副主任医师在均不知手术病理情况下进行独立阅片。结果研究发现阅片者结果与术中腹膜癌指数一致性较高,组内相关系数达0.90(95%置信区间:0.64~0.96)。读片器1(曲线下面积=0.96)和读片器2(曲线下面积=0.98)磁共振成像腹膜癌指数与术中腹膜癌指数(曲线下面积=0.92)显示与完全肿瘤细胞减灭术预测值相近。结论在晚期卵巢癌患者中PCI评分中DW-MRI可视为强有力的非侵入性选择工具,对于确定是否行完全肿瘤细胞减灭术存在较大意义。Objective:To evaluate the potential of diffusion weighted MRI in predicting peritoneal cancer index(PCI)in patients with advanced ovarian cancer and whether patients can perform complete tumor cell extinction.Materials and Methods:We retrospectively included 25 patients with advanced ovarian cancer(FIGO stage IIb and above)who received cytoreductive surgery at Dandong Traditional Chinese Medicine Hospital from June 2016 to May 2018.Included patients underwent a 1.5 T magnetic resonance diffusion-weighted imaging scan before surgery[the scan sequence in DW-MRI examination includes T1 and T2-weighted imaging sequence,contrast-enhanced T1-weighted and diffusion-weighted imaging(b=0,1000 s/mm^2)]sequence.Two associate chief radiologists performed independent reading without knowing the pathology of the operation.Results:The study found that the results of the readers were consistent with the intraoperative peritoneal cancer index,and the intra-group correlation coefficient reached 0.90(95%confidence interval:0.64—0.96).Reader 1(area under the curve=0.96)and reader 2(area under the curve=0.98)magnetic resonance imaging peritoneal cancer index and intraoperative peritoneal cancer index(area under the curve=0.92)display and complete cytoreductive surgery similar predictions.Conclusions:In patients with advanced ovarian cancer,DW-MRI can be regarded as a powerful non-invasive selection tool in the PCI score,which is of great significance for determining whether to perform complete cytoreductive surgery.

关 键 词：肿瘤细胞减灭术 扩散加权成像 磁共振成像 卵巢癌 腹膜癌 

分 类 号：R445.2[医药卫生—影像医学与核医学] R737.31[医药卫生—诊断学]