眼底自发荧光检查在特发性黄斑裂孔诊断及视力预后判定中的应用  

Applications of fundus autofluorescence on diagnosis and visual prognosis assessment of idiopathic macular hole

作　　者：岳慧芳 张蕴达[2] 张喜梅[2] Yue Huifang;Zhang Yunda;Zhang Ximei(Shanxi Medical University,Taiyuan 030001,China;Department of Retina,Shanxi Eye Hospital,Taiyuan 030002,China)

机构地区：[1]山西医科大学,太原030001 [2]山西省眼科医院视网膜科,太原030002

出　　处：《国际眼科纵览》2020年第6期413-418,共6页International Review of Ophthalmology

基　　金：山西省卫生健康委员会科技攻关计划项目(2011058);山西省应用基础研究项目青年科技研究基金(201801D221014)。

摘　　要：眼底自发荧光(fundus autofluorescence,FAF)作为一种操作简便、非侵入性的成像技术,可通过判断视网膜中脂褐质及黑色素的变化,以高/低荧光呈现视网膜功能状况。特发性黄斑裂孔(idiopathic macular hole,IMH)的FAF图像表现为黄斑裂孔高荧光区及孔周围的环形低荧光。术后裂孔完全闭合,高荧光区消失,否则表现为持续高荧光状态。FAF图像表现与相干光断层扫描图像及视力有相关性。(国际眼科纵览,2020,44:413-418)Fundus autofluorescence(FAF)is a simple and non-invasive imaging modality.This technique based on the changes of lipofuscin and melanin within the retina,gives insight into metabolic condition of retina.The FAF imaging of idiopathic macular hole(IMH)shows hyperautofluorescence corresponding to the hole area and surrounding hypoautofluorescent ring.The hyperautofluorescence can disappear or reduce due to a successful macular hole closure,or can be persistent with an unclosed hole.FAF provides valuable information about diagnosis and follow-up of IMH,combined with OCT has a great role both in vision prognosis,understanding pathogenesis and anatomical and functional recovery.(Int Rev Ophthalmol,2020,44:413-418)

关 键 词：眼底自发荧光 特发性黄斑裂孔 

分 类 号：TP3[自动化与计算机技术—计算机科学与技术]