姜黄素抗肿瘤药理作用的研究进展  

Research progress of pharmacological functions on tumor suppression by curcumin

作　　者：崔明花[1] 付二花 林贞花[1] 朴英实[1] CUI Ming-hua;FU Er-hua;LIN Zhen-hua;PIAO Ying-shi(Medical College,Yanbian University,Yanji 133002,Jilin Province,China)

机构地区：[1]延边大学医学院,吉林延吉133002

出　　处：《中国临床药理学杂志》2021年第2期186-188,196,共4页The Chinese Journal of Clinical Pharmacology

基　　金：吉林省卫生与健康青年科技骨干培养计划项目(2018Q039)。

摘　　要：姜黄素是从姜科、天南星科等植物的根茎中提取的一种酸性多酚化合物,具有良好的抗炎及抗肿瘤作用。本文针对姜黄素对肿瘤的增殖、侵袭与转移、细胞能量代谢、血管生成、凋亡、自噬、免疫调节、逆转多药耐药性等方面的抗肿瘤药理作用及分子机制做一综述。Curcumin is an acidic polyphenolic compound extracted from rhizomes of plants such as Turmeric and Araceae,which has a good anti-tumor effect.In this paper,the effects of curcumin on tumor proliferation,invasion and metastasis,cell energy metabolism,angiogenesis,apoptosis,autophagy,immune regulation,reversal of multidrug resistance and their molecular mechanisms were reviewed.

关 键 词：姜黄素 肿瘤 分子机制 

分 类 号：R28[医药卫生—中药学]