膦甲酸钠注射液致周身麻木、呼吸困难1例分析  

Cace Analysis of General Numbness and Dyspnea Caused by Foscarnet Sodium for Injection

作　　者：刘洋 马春华[1] 梁连春[1] LIU Yang;MA Chunhua;LIANG Lianchun(Department of General Infection,Beijing YouAn Hospital,Capital Medical University,Beijing 100069,China)

机构地区：[1]首都医科大学附属北京佑安医院感染综合科,北京100069

出　　处：《中国药物警戒》2021年第2期196-198,共3页Chinese Journal of Pharmacovigilance

摘　　要：目的探讨膦甲酸钠导致周身麻木、呼吸困难的机制及相关文献分析。方法我院既往诊治1例肝衰竭合并巨细胞感染患者,在应用膦甲酸钠时出现周身麻木及呼吸困难等症状,通过文献分析,探讨其发生机制,并结合该病例阐述膦甲酸钠相关不良反应概况。结果膦甲酸钠可导致周身麻木、呼吸困难,其机制可能与低钙血症相关。结论膦甲酸钠应用中应严密监测患者情况,及时发现并处理不良反应。Objective To explore the mechanism of foscarnet sodium causing general numbness and dyspnea and to analyze the related literature.Methods A case of liver failure with cytomegalovirus infection was diagnosed and treated in our hospital.The symptoms of numbness and dyspnea occurred during the application of foscarnet sodium.Through literature analysis,the mechanism of the occurrence of foscarnet sodium related adverse reactions was discussed.Results Foscarnet sodium could cause general numbness and dyspnea,which might be related to hypocalcemia.Conclusion During the application of foscarnet sodium,the patients should be closely monitored,and adverse reactions should be found and treated in time.

关 键 词：膦甲酸钠 麻木 药品不良反应 

分 类 号：R969.3[医药卫生—药理学]