Osseous Rosai-Dorfman disease of tibia in children:A case report  

作　　者：Djandan Tadum Arthur Vithran Jian-Zhou Wang Feng Xiang Jie Wen Sheng Xiao Wen-Zhong Tang QianChen 

机构地区：[1]Department of Pediatric Orthopedic,Hunan Provincial People's Hospital,the First Affiliated Hospital of Hunan Normal University,Changsha 410013,Hunan Province,China

出　　处：《World Journal of Clinical Cases》2021年第6期1416-1423,共8页世界临床病例杂志

基　　金：Supported by Natural Science Foundation of Hunan Province,China,No.2019JJ50324.

摘　　要：BACKGROUND Rosai-Dorfman disease(RDD),or sinus histiocytosis with massive lymphadenopathy,is a benign histiocytic disorder.Extranodal involvement is common,occurring in>40%of patients,but bone involvement occurs in<10%of cases.In addition,primary bone RDD is extremely rare.The majority of patients are adolescents and young adults,and the mean age at onset is 20-years-old.CASE SUMMARY We report an 8-year-old Chinese girl who presented to our hospital with an insidious onset of swelling and pain in the middle shaft of her right tibia for 4 mo.We performed total surgical resection of the right tibia lesion and allograft transplantation.A good prognosis was confirmed at the 6 mo follow-up.Pain and swelling symptoms were totally relieved,range of motion of her right knee and ankle returned to normal,and there was no clinical evidence of lesion recurrence at last follow up.Our case is the second reported case of osseous RDD without lymphadenopathy in the shaft of the tibia of a child.CONCLUSION Extranodal RDD is a rare disease and can be misdiagnosed easily.Lesion resection and allograft transplantation are an option to treat extranodal RDD in children with good short term result.Pediatric orthopedist should be aware of this rare disease,especially extranodal involvement.

关 键 词：Osseous Rosai-Dorfman disease Children tibia pain and swelling Lesion resection Allograft transplantation Good prognosis Rare benign disorder Case report 

分 类 号：R726.8[医药卫生—儿科]