Visible light-induced hydroxyalkylation of 2H-benzothiazoles with alcohols via selectfluor oxidation  

作　　者：Yaolei Kong Wenxiu Xu Xinghai Liu Jianquan Weng 

机构地区：[1]College of Chemical Engineering,Zhejiang University of Technology,Hangzhou 310014,China

出　　处：《Chinese Chemical Letters》2020年第12期3245-3249,共5页中国化学快报（英文版）

基　　金：the financial support by the National Natural Science Foundation of China(No.30900959);the Natural Science Foundation of Zhejiang Province(No.LY17C140003)。

摘　　要：A visible-light induced metal-free approach was described for the hydroxyalkylation of 2 Hbenzothiazoles with alcohols by using selectfluor as the oxidant.A variety of 2 H-benzothiazoles and alcohols could be tolerated,providing a mild and simple method for the synthesis of C2-hydroxyalkylated2 H-benzothiazoles in moderate to good yields.Besides,ethers were also compatible in this reaction,leading to corresponding C2 ether-substituted 2 H-benzothiazoles with high regioselectivity.

关 键 词：Visible light-induced HYDROXYALKYLATION 2H-Benzothiazole Alcohol SELECTFLUOR 

分 类 号：O626[理学—有机化学]