298例儿童呼吸系统疾病抗菌药物应用情况探究  

Investigation into the use of antibiotics in the treatment of 298 children with respiratory diseases

作　　者：王桂玲[1] 耿雨作 王媛媛[1] 段昌丰 李江全[2] WANG Guiling;GENG Yuzuo;WANG Yuanyuan;DUAN Changfeng;LI Jiangquan(Pediatric Department of Suqian TCM Hospital,Suqian 223800,China)

机构地区：[1]宿迁市中医院儿科,江苏宿迁223800 [2]江苏省中医院儿科,南京210000

出　　处：《中国中西医结合儿科学》2021年第1期80-84,共5页Chinese Pediatrics of Integrated Traditional and Western Medicine

基　　金：江苏省中医药科技计划项目(YB2017087);宿迁市重大科技研发项目(S201701)。

摘　　要：目的了解本地区儿科呼吸系统疾病抗菌药物的应用现状,探寻行之有效的管理和干预办法。方法收集2017年12月至2019年1月间于宿迁市中医院就诊的298例呼吸系统疾病患儿的就诊资料,并加以分析。结果298例患儿中,急性上呼吸道感染抗菌药物使用率占63.2%,气管支气管炎抗菌药物使用率达83.9%,差异有统计学意义(P<0.01)。298例呼吸系统疾病抗菌药物总使用率为85.2%,口服抗菌药物占62.2%,注射抗菌药物占50.8%。处方常见的抗菌药物为头孢菌素类(63.4%)、青霉素类(41.3%)、大环内酯类(31.8%)、其他(7.0%)等。单用一种抗菌药物者占61.4%,二者联用30.8%,三联和四联分别为7.4%和0.3%,差异有统计学意义(P<0.01)。结论本地区儿童呼吸系统疾病中抗菌药物的使用仍存在不合理之处,表现在用药指征、给药途径、品种选择、联合用药等方面的不足。提高抗菌药物耐药的意识,组织教育和培训,加强基层医疗建设和监管力度仍非常重要。Objective To investigate the application of antibacterial medicines in pediatric respiratory diseases to search for effective ways of management and intervention.Methods The medical records of 298 children with respiratory diseases treated in Suqian TCM Hospital from December 2017 to January 2019 were collected and analyzed.Results Among the 298 cases,the utilization rate of antibiotics in children with acute upper respiratory tract infection was 63.2%,and that in children with tracheal bronchitis reached 83.9%,the difference being statistically significant(P<0.01).Among the 298 cases,the total utilization rate of antibacterial drugs was 85.2%,that of oral antibacterial drugs was 62.2%,and that of injection antibacterial drugs was 50.8%.The common antibiotics prescribed were cephalosporins(63.4%),penicillins(41.3%),macrolides(31.8%),and others(7.0%),etc.About 61.4%of patients were treated with one antibacterial drug alone,30.8%with two combined drugs,7.4%with three combined drugs and 0.3%with four combined drugs,respectively,and the difference was statistically significant(P<0.01).Conclusion The use of antimicrobial agents in children's respiratory diseases in this region is not very reasonable,which is manifested in the deficiency in drug indication,route of administration,variety selection and combination of drugs.It is still very important to raise awareness of antimicrobial resistance,organize education and training,and strengthen the construction and supervision of primary health care.

关 键 词：呼吸系统疾病 抗菌药物 应用现状 儿童 

分 类 号：R725.6[医药卫生—儿科]