新型冠状病毒肺炎患者347例实验室检测结果分析  

Analysis of laboratory test results of 347 patients with COVID-19

作　　者：刘子砚[1] 牛志杰 井沆[1] 武红权[1] LIU Ziyan;NIU Zhijie;JING Hang;WU Hongquan(Department of laboratory Test,Guizhou Provincial People′s Hospital,Guiyang,Guizhou 550002,China)

机构地区：[1]贵州省人民医院检验科,贵州贵阳550002

出　　处：《现代医药卫生》2021年第4期572-575,共4页Journal of Modern Medicine & Health

摘　　要：目的探讨新型冠状病毒肺炎(COVID-19)患者的实验室检查指标特点,为临床诊疗提供依据。方法收集2020年2月10日至3月4日于鄂州市第三医院和鄂州市雷山医院住院治疗的347例COVID-19确诊患者的实验室检查结果,分析各检测指标水平及特点。结果COVID-19患者男女比例为1.08∶1,平均年龄(52.9±15.1)岁。实验室检查结果中,白细胞计数(WBC)(99.71%)、中性粒细胞绝对值(NEUT)(95.68%)正常或减少,嗜酸性粒细胞绝对值(EOS)(17.87%)减少,淋巴细胞绝对值(LYMPH)(30.84%)减少,中性粒细胞与淋巴细胞比值(NEUT/LYMPH)(36.31%)升高;全程C反应蛋白(FR-CRP)(18.44%)升高,降钙素原(PCT)水平未见明显异常;清蛋白(Alb)(47.55%)降低,谷丙转氨酶(ALT)(30.55%)、谷草转氨酶(AST)(21.61%)、谷氨酰转肽酶(GGT)(24.21%)、乳酸脱氢酶(LDH)(20.46%)水平升高,总胆红素(TB)、直接胆红素(DB)、间接胆红素(IB)均无明显异常;纤维蛋白原(Fbg)(20.28%)、D-二聚体(44.06%)均升高。结论COVID-19患者见于各年龄段男女人群,除核酸检测和影像学检查外,血常规、生化指标及凝血机制结果可辅助临床医生进行诊疗,中青年患者ALT、GGT、Fbg、D-D水平均升高,应密切监测,及时调整治疗方案。Objective To conclude the changes of laboratory results of novel corona virus disease 2019(COVID-19)confirmed patients.So as to provide bases of clinical diagnosis and treatment.Methods The laboratory test results of 347 patients with confirmed COVID-19 who were hospitalized in Ezhou Third Hospital and Ezhou Leishan Hospital on February 10,2020 and March 4,2020 were collected to analyze the level and characteristics of each test index.Results The male to female ratio of COVID-19 patients was 1.08∶1,and the mean age was(52.9±15.1)years.The results of laboratory examination showed that the white blood cell count(WBC)(99.71%),absolute neutrophils(NEUT)(95.68%)were normal or decreased,the absolute value of eosinophiles(EOS)(17.87%)decreased,absolute value of lymphocytes(30.84%)decreased and the neutrophils/lymphocytes ratio(NEUT/LYMPH)(36.31%)increased.The C-reactive protein(FR-CRP)(18.44%)increased throughout the whole process,and the level of procalcitonin(PCT)was not significantly abnormal.Albumin(47.55%)was decreased,alanine aminotransferase(ALT)(30.55%),aspartate aminotransferase(AST)(21.61%),glutamyl transpeptidase(GGT)(24.21%),lactate dehydrogenase(LDH)(20.46%)were increased,total bilirubin(TB),direct bilirubin(DB),indirect bilirubin(IB)were not abnormal.Fibrinogen(FBG)(20.28%)and D-dimer(44.06%)increased.Conclusion All ages of male or female can be infected with SARS-CoV-2.Besides viral nucleic acid testing and CT scans,results of blood routine,clinical biochemical tests and blood coagulation tests can also assist clinical diagnosis and treatment.Results of ALT、GGT、Fbg、D-D increased in young and mid-age adults should be paid attention to and adjust treatments in time.

关 键 词：新型冠状病毒 新型冠状病毒肺炎 实验室检查指标 

分 类 号：R115[医药卫生—公共卫生与预防医学] R446.1[医药卫生—诊断学]