无锡-常州地下水中内分泌干扰物的赋存特征和健康风险评价  

Occurrence Characteristics and Health Risk Assessment of Endocrine Disrupting Chemicals in Groundwater in Wuxi-Changzhou

作　　者：王淑婷 饶竹[1] 郭峰 刘成海 战楠 王娅南 彭洁 杨鸿波 WANG Shu-ting;RAO Zhu;GUO Feng;LIU Cheng-hai;ZHAN Nan;WANG Ya-nan;PENG Jie;YANG Hong-bo(Key Laboratory of Eco-geochemistry(Ministry of Natural Resources),National Research Center for Geoanalysis,Chinese Academy of Geological Sciences,Beijing 100037,China;School of Public Health,Guizhou Medical University,Guiyang 550025,China)

机构地区：[1]中国地质科学院国家地质实验测试中心,自然资源部生态地球化学重点实验室,北京100037 [2]贵州医科大学公共卫生学院,贵阳550025

出　　处：《环境科学》2021年第1期166-174,共9页Environmental Science

基　　金：国家自然科学基金项目(21976044,21966011);中央公益性科研院所基本科研业务费专项(CSJ201906);中国地质调查局地质调查项目(DD20189627);国家国际科技合作项目(2015DFA41280)。

摘　　要：采用固相萃取-超高效液相色谱串联质谱法(SPE-UPLC-MS/MS)分析了无锡-常州地区地下水中4类(性激素、孕激素、糖皮质激素和酚类激素)22种典型内分泌干扰物(EDCs)的赋存特征.结果表明,共有20种EDCs被检出,以双酚A(BPA)、雌酮(E1)、雌二醇(E2)和炔雌醇(EE2)为主,检出率均在90%以上,其次是雌三醇(E3)和甲基泼尼松龙(Meprednl),检出率分别为67.7%和48.4%.BPA平均浓度最高,为4.95 ng·L^(-1),其次是甲基泼尼松龙、雌二醇、泼尼松龙(Prednl)、丙酸睾酮(TES-pro)和醋酸甲地孕酮(MA),平均浓度分别为2.84、0.71、0.64、0.58和0.53 ng·L^(-1).各点位总浓度范围在0.38~147.35 ng·L^(-1)之间,高浓度点主要集中在常州市新北区、溧阳市和钟楼区.结合主成分分析(PCA)和采样点周边污染源对潜在来源进行解析,结果表明地下水中EDCs主要来源于生活污水、养殖和工业废水,其次为医疗废水.非致癌健康风险评价结果表明,研究区地下水中EDCs非致癌风险整体处于较低水平,饮水途径引起的风险水平大于皮肤暴露,EE2的非致癌风险最高,应作为重点监控对象.The concentrations of 22 endocrine disrupting chemicals,including 4 categories of sex hormones,progesterones,glucocorticoids,and phenolic hormones,in groundwater of Wuxi-Changzhou were analyzed using solid-phase extraction and ultraperformance liquid chromatography tandem mass spectrometry.The results indicated that 20 EDCs were detected,among which bisphenol A(BPA),estrone(E1),estradiol(E2),and 17α-ethinyl estradiol(EE2)were the main components with detection ratios greater than 90%,followed by estriol(E3)and methyl-prednisolonel(Meprednl),which had detection rates 67.7%and 48.4%,respectively.The average concentration of BPA was the highest(4.95 ng·L^(-1)),followed by that of Meprednl,E2,prednisolone(Prednl),testosterone propionate(TES-pro),and megestrol-acetate(MA;2.84,0.71,0.64,0.58,and 0.53 ng·L^(-1),respectively).The total concentration in each site ranged from 0.38 to 147.35 ng·L^(-1).The sites with higher concentration were mainly distributed in the Xinbei District,Liyang City,and the Zhonglou District of Changzhou City.The potential sources were analyzed by a principal component analysis(PCA)combining the point sources near sample sites.The results showed that domestic sewage,aquaculture,and industrial wastewater were the main sources,following by medical wastewater.A non-carcinogenic risk assessment showed a low risk of EDCs in the groundwater of the study area,and the risk of drinking water was greater than that of skin exposure.EE2 had the highest non-carcinogenic risk and is suggested to be monitored in priority.

关 键 词：内分泌干扰物 无锡-常州地区 地下水 赋存特征 健康风险 

分 类 号：X523[环境科学与工程—环境工程]