多糖的药代动力学研究进展  

Progress in pharmacokinetics of polysaccharides

作　　者：徐鑫[1] 王睿[2] 高建[3] 彭金咏[1] 李华[1] 王丽[1] XU Xin;WANG Rui;GAO Jian;PENG Jinyong;LI Hua;WANG Li(College of Pharmacy,Dalian Medical University,Dalian 116044,Liaoning,China;Department of Hematology,the Second Hospital of Dalian Medical University,Dalian 116027,Liaoning,China;Department of Pharmacy,the Second Affiliated Hospital of Dalian Medical University,Dalian 116027,Liaoning,China)

机构地区：[1]大连医科大学药学院,辽宁大连116044 [2]大连医科大学附属第二医院血液科,辽宁大连116027 [3]大连医科大学附属第二医院药学部,辽宁大连116027

出　　处：《中国临床药理学与治疗学》2021年第2期230-235,共6页Chinese Journal of Clinical Pharmacology and Therapeutics

基　　金：辽宁省“兴辽英才计划”项目(XLYC1808031);大连市科技创新基金项目(2019J12SN58)。

摘　　要：多糖是大多数中药材的主要成分之一。近年来,多糖的功效逐渐成为生命科学领域研究的热点,然而其药代动力研究尚处于起步阶段。本文对多糖的分类、生物分析方法、药代动力学研究进展进行综述,以期为多糖药代动力学的进一步研究提供参考。Polysaccharide(PS)is one of the principal constituents in most traditional Chinese medicine.In recent years,the efficacy of PS has gradually become a popular aspect in fields of life science.Meanwhile,its pharmacokinetic research is still in its infancy.The classification,bioanalytical methods and pharmacokinetics of PS in recent years are summarized in this review.We hope to provide reference and guidance for researchers to study the pharmacokinetics of PS.

关 键 词：多糖 生物分析方法 药代动力学 

分 类 号：R969[医药卫生—药理学]