多囊卵巢综合征患者雄激素与代谢表型关系研究进展  

Research progress in relationship between androgen and metabolic phenotype in patients with polycystic ovary syndrome

作　　者：杨爽清 程静[1] Yang Shuangqing;Cheng Jing(The Second Affiliated Hospital of Wenzhou Medical University,Wenzhou 325000,China)

机构地区：[1]温州医科大学附属第二医院,325000

出　　处：《中华生殖与避孕杂志》2020年第12期1031-1037,共7页Chinese Journal of Reproduction and Contraception

摘　　要：多囊卵巢综合征(polycystic ovary syndrome,PCOS)是育龄期女性常见生殖内分泌疾病,不仅影响生殖,还与代谢紧密联系。雄激素过多是PCOS重要特征,糖脂代谢异常是PCOS患者常见的代谢紊乱。PCOS的雄激素过多和胰岛素抵抗相互关联,两者又与脂代谢异常有关。三者之间的紧密联系影响PCOS的发生发展过程。临床上对PCOS患者代谢异常的早期发现和有效治疗对PCOS患者远期并发症的预防具有重要意义。本文将从PCOS中的雄激素过多、PCOS代谢异常原因及两者间潜在联系和治疗等方面做一综述。Polycystic ovary syndrome(PCOS)is a common reproductive endocrine disease in women of reproductive age,which not only affects reproduction,but also has a close relationship with metabolism.Androgen excess is an important characteristic,and abnormal glucose and lipid metabolism are common metabolic disorders in PCOS women.Androgen excess is correlated with insulin resistance in PCOS,which is also associated with dyslipidemia.The close link among the three factors promotes the occurrence and development of PCOS.Early screen and control of metabolic abnormalities would be beneficial for the complication prevention for PCOS patients for long term.In this paper,we discussed androgen excess,metabolic abnormalities and their relationship,as well as treatment in PCOS.

关 键 词：雄激素 多囊卵巢综合征 胰岛素抵抗 脂代谢 

分 类 号：R711.75[医药卫生—妇产科学]