网络药理学在传统中、蒙、藏药治疗骨关节退变性疾病中的研究进展  

RESEARCH PROGRESS OF NETWORK PHARMACOLOGY IN THE TREATMENT OF BONE AND JOINT DEGENERATIVE DISEASES WITH TRADITIONAL CHINESE,MONGOLIAN AND TIBETAN MEDICINE

作　　者：薛建民 杨学军[2] XUE Jian-min;YANG Xue-jun(Inner Mongolia Medical University,Hohhot 010059 China)

机构地区：[1]内蒙古医科大学,内蒙古呼和浩特010059 [2]内蒙古医科大学第二附属医院胸腰椎脊柱外科

出　　处：《内蒙古医科大学学报》2021年第1期104-107,共4页Journal of Inner Mongolia Medical University

摘　　要：在我国腰椎间盘突出症等骨关节退行性疾病已成为中老年人群中的常见病和多发病,给社会造成沉重的经济负担。内蒙古特色蒙药那如三味丸在治疗腰椎间盘突出症等骨关节退变性疾病中取得良好效果,但是具体的药物作用机制还有待明确。网络药理学是依托于系统生物学发展而来的新兴学科,其系统性、多效性、多靶点出发分析药物药理作用的特点非常适用于中药、蒙药、藏药等传统复方方剂的药理机制、作用靶点以及相关通路的研究。本文就近年来网络药理学用于中药、蒙药、藏药的药理机制研究做一综述。In China,bone and joint degenerative diseases such as lumbar disc herniation have become common and frequently-occurring diseases in the middle-aged and elderly,causing a heavy economic burden to the society.Inner Mongolia characteristic Mongolian medicine Naru Sanwei Pill has achieved good results in the treatment of bone and joint degenerative diseases such as lumbar disc herniation,but the specific drug mechanism remains to be determined.Network pharmacology is a new discipline based on the development of system biology.its systematic,multi-effect and multi-target analysis of the characteristics of drug pharmacology is very suitable for the study of pharmacological mechanism,action targets and related pathways of traditional compound prescriptions such as traditional Chinese medicine,Mongolian medicine,Tibetan medicine and so on.This paper reviews the pharmacological mechanism of network pharmacology in traditional Chinese medicine,Mongolian medicine and Tibetan medicine in recent years.

关 键 词：那如三味丸 腰椎间盘突出症 腰椎退行性病变 网络药理学 

分 类 号：R684.3[医药卫生—骨科学]