竹叶石膏汤辅助治疗感染性心内膜炎临床观察  

Analysis on the Effect of Zhuye Shigao Decoction in the Adjuvant Treatment of Infectious Endocarditis

作　　者：杨栋强[1] 康谊[1] 丁岗强[1] 毛重山[1] 陈芳[2] YANG Dongqiang;KANG Yi;DING Gangqiang;MAO Zhongshan;CHEN Fang(Department of Infection,Henan Province People’s Hospital,Henan Province,Zhengzhou 450003,China;Basic Medical College,Henan University of Traditional Chinese Medicine,Henan Province,Zhengzhou 450046,China)

机构地区：[1]河南省人民医院感染科,河南郑州450003 [2]河南中医药大学基础医学院,河南郑州450046

出　　处：《光明中医》2021年第2期165-167,共3页GUANGMING JOURNAL OF CHINESE MEDICINE

基　　金：国家自然科学基金(No.81904050)。

摘　　要：目的探究竹叶石膏汤治疗感染性心内膜炎的临床效果。方法选取收治的感染性心内膜炎患者80例,按随机数字表法将其分为对照组(40例)和观察组(40例)。对照组给予西医治疗,观察组在此基础上给予竹叶石膏汤辅助治疗。比较2组的治疗效果。结果治疗后观察组与对照组的临床总有效率分别为82.50%、62.50%,观察组显著高于对照组(P<0.05);与治疗前比,2组治疗后血氧分压(p (O_(2)))、氧合指数(p(O_(2))/Fi(O_(2)))均显著升高,且观察组高于对照组(P<0.01),但二氧化碳分压(p(CO_(2)))显著降低(P<0.05);治疗后观察组中医证候总有效率显著高于对照组(P<0.05)。结论竹叶石膏汤辅助治疗可有效缓解感染性心内膜炎患者临床症状,改善血气指标,值得临床推广应用。Objective To explore the clinical effect of Zhuye Shigao decoction on infective endocarditis.Methods 80 patients with infective endocarditis were selected and divided into control group(n=40) and observation group(n=40) according to random number table.The control group was treated with Western medicine,while the observation group was treated with Zhuye Shigao decoction.The therapeutic effects of the two groups were compared.Results After treatment,the total clinical effective rates of the observation group and the control group were82.50% and 62.50%,respectively.The total clinical effective rate of the observation group was significantly higher than that of the control group(P<0.05).Compared with before treatment,the partial pressure of p(O_(2)) and p(O_(2))/Fi(O_(2)) in both groups increased significantly after treatment,and the control group is lower than the observation group(P<0.01),but the partial pressure of p(CO_(2)) decreased significantly(P<0.05).After treatment,the total effective rate of TCM syndromes in the observation group was significantly higher than that in the control group(P<0.05).Conclusion The Zhuye Shigao decoction in the adjuvant treatment of infectious endocarditis can effectively alleviate the clinical symptoms of infective endocarditis and improve the blood gas index,which is worthy of clinical application.

关 键 词：心悸 感染性心内膜炎 竹叶石膏汤 中医药疗法 经方 

分 类 号：R259[医药卫生—中西医结合]