小儿定喘口服液辅助治疗小儿支气管肺炎的疗效及其对炎症因子的影响  

Efficacy of the adjuvant therapy of Pediatric Dingchuan Oral Liquid against bronchopneumonia in children and its influence on inflammatory factors

作　　者：冯宏达 FENG Hongda(Department of Pediatrics,the Central Hospital of Jiamusi City in Heilongjiang Province,Jiamusi 154002,China)

机构地区：[1]黑龙江省佳木斯市中心医院儿科,黑龙江佳木斯154002

出　　处：《中国现代医生》2021年第2期60-62,共3页China Modern Doctor

摘　　要：目的探讨小儿定喘口服液辅助治疗小儿支气管肺炎的疗效及其对炎症因子的影响。方法选取2018年10月至2019年11月我院收治的124例小儿支气管肺炎患儿,按照随机数字表法分为对照组与观察组,每组各62例。对照组采用常规治疗,观察组则在常规治疗基础上应用小儿定喘口服液辅助治疗。观察两组患儿的临床指标、治疗效果及血清炎性因子IL-6、TNF-α的表达。结果观察组患儿气喘时间、发热时间、肺部啰音消失时间、住院时间、X线阴影消失时间均明显低于对照组(P<0.05)。观察组患儿治疗总有效率(96.77%)高于对照组(85.48%),差异有统计学意义(P<0.05)。两组患儿治疗前血清IL-6、TNF-α水平比较,差异无统计学意义(P>0.05),治疗后两组患儿血清IL-6、TNF-α均有所下降,但观察组下降水平优于对照组(P<0.05)。结论应用小儿定喘口服液辅助治疗小儿支气管肺炎疾病效果显著,能有效改善患者的血清炎症因子水平。Objective To explore the efficacy of the adjuvant therapy of Pediatric Dingchuan Oral Liquid for children against bronchopneumonia in children and its influence on inflammatory factors.Methods A total of 124 children with bronchopneumonia admitted to and treated in our hospital from October 2018 to November 2019 were selected as the subjects of research.According to the random number table method,they were divided into the control group and the observation group,with 62 children in each group.The control group received routine treatment,while the observation group received the adjuvant therapy of Pediatric Dingchuan Oral Liquid on the basis of routine treatment.The clinical indexes,curative effects and expressions of serum inflammatory factors IL-6 and TNF-α of the two groups were statistically compared.Results The asthma time,fever time,pulmonary rales disappearance time,hospitalization time and X-ray shadow disappearance time of the children in the observation group were significantly shorter than those in the control group(P<0.05).The total effective rate of treatment(96.77%)of the children in the observation group was higher than that in the control group(85.48%),and the difference was statistically significant(P<0.05).There was no significant difference in serum IL-6 and TNF-α levels between the two groups before treatment(P>0.05),and after treatment,the serum IL-6 and TNF-αlevels of the children in the two groups all decreased,but the decrease level of the observation group was superior to that of the control group(P<0.05).Conclusion The adjuvant therapy of Pediatric Dingchuan Oral Liquid against the disease of bronchopneumonia in children has significant efficacy.It can effectively ameliorate the level of serum inflammatory factors in patients.

关 键 词：小儿定喘口服液 小儿支气管 白介素-6 肿瘤坏死因子-Α 

分 类 号：R272[医药卫生—中医儿科学]