稀土金属催化的碳氢官能团化反应  

Rare-Earth Metal-Catalyzed C-H Functionalization

作　　者：苏健洪 徐信 Su Jianhong;Xu Xin(College of Chemistry,Chemnical Engineering and Materials Science,Soochow University,Suzhou 215123,China)

机构地区：[1]苏州大学材料与化学化工学部,江苏苏州215123

出　　处：《中国稀土学报》2021年第1期171-180,共10页Journal of the Chinese Society of Rare Earths

基　　金：国家自然科学基金面上项目(21871204)资助。

摘　　要：过渡金属催化的碳氢官能团化反应具有原子经济性高、区域选择性好和合成路线简短等优点,近年来得到了化学家们的广泛关注,是当前有机合成化学的热门研究领域之一。近几年来,稀土金属催化剂也逐渐被开发应用于该领域,得到优异的结果,同时也表现出一些独特的催化活性。本文综述了稀土金属络合物催化的碳氢官能团化反应,主要包括C-H烷基化反应以及C-Hβ-胺烷基化反应,这些反应为C-C键的构筑提供了新方法。同时本文也针对该领域目前存在的挑战,对未来的研究工作做了展望。Transition metal-catalyzed C-H functionalization has recently attracted extensive attention and become one of the most flourished areas in the synthetic organic chemistry, because it offers a regioselective and atom-and step-economical method to various organic molecules. In recent years, rare-earth(RE) metal-based catalysts have been successfully applied in this field, showing some excellent results and unique properties. In this review, RE-catalyzed C-H functionalization reactions were briefly summarized, mainly including C-H alkylation and C-H β-aminomethylation which provide new methods for the construction of C-C bonds. Meanwhile, currently unmet challenges and the suggested future directions in this research filed are also presented.

关 键 词：稀土 催化反应 有机合成 碳氢官能团化 σ键复分解 

分 类 号：O62[理学—有机化学]