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作 者:张子雨 宋敏[2] 肖贵宝[3] 廖兰凯 杨勇 ZHANG Ziyu;SONG Min;XIAO Guibao;LIAO Lankai;YANG Yong(School of Medicine,University of Electronic Science and Technology of China,Chengdu 610054,China;Department of Pharmacy,the First People’s Hospital of Ziyang,Sichuan Ziyang 641300,China;Department of Infectious Diseases,the First People’s Hospital of Ziyang,Sichuan Ziyang 641300,China;Department of Critical Care Medicine,the First People’s Hospital of Ziyang,Sichuan Ziyang 641300,China;Department of Pharmacy,Sichuan Academy of Medical Science and Sichuan Provincial People’s Hospital,Chengdu 610054,China)
机构地区:[1]电子科技大学医学院,成都610054 [2]资阳市第一人民医院药剂科,四川资阳641300 [3]资阳市第一人民医院感染性疾病科,四川资阳641300 [4]资阳市第一人民医院重症医学科,四川资阳641300 [5]四川省医学科学院·四川省人民医院药学部,成都610054
出 处:《药学服务与研究》2021年第1期45-51,共7页Pharmaceutical Care and Research
基 金:四川省卫生健康委员会医学重大创新项目(20ZDCX002)。
摘 要:目的:回顾性分析四川省资阳地区确诊为新型冠状病毒肺炎(Corona Virus Disease-2019,COVID-19)患者治疗用药的有效性和安全性。方法:选取在资阳市第一人民医院使用了抗病毒药物、抗菌药物、糖皮质激素类药物等药物的3例COVID-19患者作为研究对象,对其用药进行分析。结果:3例患者经过多种药物联合治疗后临床症状、体征基本消失,非同日连续两次核酸检测为阴性,治愈出院。结论:在缺乏COVID-19大型临床试验数据的背景下,参考相关指南及专家共识,科学、规范地个体化给药,有利于减少不合理用药的情况出现。Objective:To retrospectively analyze the medication efficacy and safety in the patients diagnosed to have Corona Virus Disease-2019(COVID-19)in Ziyang District of Sichuan Province.Methods:Three COVID-19 patients treated with antiviral and antibacterial drugs plus glucocorticoids and other drugs in the First People’s Hospital of Ziyang were selected as study subjects,and careful analysis was made on the medication in these patients.Results:The clinical symptoms and signs of the 3 patients generally disappeared after combined treatment with multiple drugs,and 2 nucleic acid tests were shown to be negative in the 2 non-consecutive days.Evidence proved that they were cured and discharged from hospital.Conclusion:In the context of lacking medical data from large clinical trials of COVID-19 and with reference to related guidelines and expert consensus,rational,standardized and individualized medication is beneficial to the reduction of the occurrence of irrational medication.
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