上海市老年人群血钠含量与糖尿病的相关性研究  

Correlation between serum sodium level and diabetes in elderly population in Shanghai

作　　者：赵侃洁 刘畅 张玉珍 郑亮[1,3] 华一飞 ZHAO Kan-jie;LIU Chang;ZHANG Yu-zhen;ZHENG Liang;HUA Yi-fei(Department of Preventive Medicine,Tongji University School of Medicine,Shanghai 200120,China;Xuhui District Xietu Community Health Service Center,Shanghai 200030,China;Research Center for Translational Medicine,Key Laboratory of Arrhythmias,Ministry of Education,Shanghai East Hospital,Tongji University School of Medicine,Shanghai 310000,China;Department of Cardiovascular Surgery,Shanghai East Hospital,Tongji University School of Medicine,Shanghai 310000,China)

机构地区：[1]同济大学医学院预防医学教研室,上海市200120 [2]徐汇区斜土社区卫生服务中心 [3]同济大学附属东方医院转化医学平台(教育部重点实验室) [4]同济大学附属东方医院心脏外科

出　　处：《中国心血管病研究》2021年第2期138-141,共4页Chinese Journal of Cardiovascular Research

基　　金：中央高校基本科研业务专项资金(22120180337);上海市科委重点项目(17431906600);浦东新区临床高峰学科(PWYgf2018-05)。

摘　　要：目的评估上海市老年社区糖尿病患者人群中血钠含量与糖尿病之间的相关性。方法于2017年6~10月间,在上海市浦东新区高行社区符合纳人排除标准的老年人群进行了整群随机抽样,并行回顾性调查分析。采用简单线性相关分析血钠含量与糖尿病之间的相关性;采用Logistic回归模型来评估导致糖尿病高发的危险因素。结果在1739名研究对象中,糖尿病患病率约为45.55%。血钠与糖化血红蛋白和空腹血糖均呈中等负相关(P<0.05)。Logistic回归模型提示,体重指数升高(OR=1.12,95%CI 1.08~1.16)是糖尿病的危险因素,而女性(0.75,95%CI 0.57~0.98)和血钠水平升高(OR=0.77,95%CI 0.73~0.82)是其保护因素。结论血钠水平与糖尿病存在一定关联,体重指数升高、血钠水平降低以及男性可能是导致糖尿病的独立危险因素。Objective To assess the association between serum sodium concentration and diabetes among the elderly community population in Shanghai.Methods A cluster random sampling was used to select subjects from the elderly in the Gaohang community of Shanghai Pudong New Area during June and October 2017.Simple linear correlation was used to analyze the correlation between serum sodium concentration and diabetes.Logistic regression models were used to assess the possible risk factors for high prevalence of diabetes.Results The prevalence of diabetes was approximately 45.55%in 1739 study subjects.The serum sodium concentration was moderately negatively correlated with glycated hemoglobin and fasting glucose(P<0.05).Logistic regression models suggested that high body mass index(OR=1.12,95%CI 1.08-1.16)was a risk factor for diabete,while female(0.75,95%CI 0.57-0.98)and high serum sodium concentrations(OR=0.77,95%CI 0.73-0.82)were protective factors.Conclusion There is an association between serum sodium concentration and diabetes;high body mass index,low serum sodium concentrations and male may be the independent risk factors for diabetes in the elderly.

关 键 词：血钠含量 糖尿病 患病率 危险因素 

分 类 号：R587.1[医药卫生—内分泌]