云浮地区6880例住院患儿急性呼吸道感染病毒病原学分析  

Analysis of viral etiology of 6880 hospitalized children with acute respiratory infection in Yunfu Area

作　　者：覃超强 丁永星 袁炜华 QIN Chao-qiang;DING Yong-xing;YUAN Wei-hua(Department of Pediatrics,Yunfu People’s Hospital,Yunfu 527300,China)

机构地区：[1]广东省云浮市人民医院儿科,527300

出　　处：《中国实用医药》2021年第4期20-25,共6页China Practical Medicine

摘　　要：目的回顾分析云浮市人民医院6880例儿科住院患儿急性呼吸道感染常见呼吸道病毒检测结果 ,了解其感染特点。方法回顾性分析2015年1月~2019年12月云浮市人民医院儿科住院的6880例急性呼吸道感染患儿的临床资料,所有患儿入院后均需做咽拭子检查,采用直接免疫荧光法检测7种常见呼吸道病毒[呼吸道合胞病毒(RSV)、甲型流感病毒(IFA)、乙型流感病毒(IFB)、腺病毒(ADV)、副流感病毒1型(PIV1)、副流感病毒2型(PIV2)、副流感病毒3型(PIV3)]。统计分析患儿的基本情况,比较不同年份、不同性别、不同年龄、不同月份、不同疾病患儿的病毒(RSV、IFA、IFB、ADV、PIV1、PIV2、PIV3)检出情况。结果 6880例住院患儿检出病毒1676例,占比为24.36%(1676/6880),病毒检出例数从高到低依次为:RSV 834例(12.12%), ADV 222例(3.23%), IFA 217例(3.15%), PIV3 184例(2.67%),IFB 122例(1.77%), PIV1 75例(1.09%), PIV2 22例(0.32%)。每年的病毒检出率从低到高依次为:2015年18.67%(256/1371), 2016年21.12%(323/1529), 2017年25.84%(379/1467), 2018年26.91%(360/1338), 2019年30.47%(358/1175)。同一年份不同病毒检出率比较,差异具有统计学意义(P<0.05);除RSV、PIV1外,不同年份同一病毒检出率比较,差异具有统计学意义(P<0.05)。各年份RSV检出率均高于其他六种病毒,差异具有统计学意义(P<0.05);IFB在2016年检出例数最多, IFA在2017年检出例数最多, ADV、PIV3在2019年检出例数最多。4443例男性患儿中检出病毒1145例, 2437例女性患儿中检出病毒531例,不同性别患儿RSV、IFA、IFB、ADV、PIV1、PIV2、PIV3检出率比较,差异无统计学意义(P>0.05)。6880例住院患儿中,≤28 d、29 d~1岁, 1~3岁, 3~6岁, 6~14岁的病毒检出率分别为21.74%(50/230)、30.37%(683/2249)、23.54%(485/2060)、20.39%(310/1520)、18.03%(148/821);<6岁患儿的病毒检出例数最多,为1528例,占91.17%;其中, 29 d~3岁患儿病毒检出1168例,占69.69%, 29 d~1岁患儿病毒�Objective To retrospectively analyze the detection results of common respiratory viruses in 6880 pediatric inpatients with acute respiratory tract infection in Yunfu People’s Hospital,and to understand the characteristics of the infection.Methods A retrospective analysis was made on the clinical data of 6880 children with acute respiratory infections hospitalized in the Department of Pediatrics of Yunfu People’s Hospital from January 2015 to December 2019.All children were required to take a throat swab after admission,and use direct immunofluorescence to detect 7 common respiratory viruses[respiratory syncytial virus(RSV),influenza A virus(IFA),influenza B virus(IFB),adenovirus(ADV),parainfluenza virus type 1(PIV1),parainfluenza virus type 2(PIV2),parainfluenza virus type 3(PIV3)].The basic situation of children was collected and analyzed,and the detection of viruses(RSV,IFA,IFB,ADV,PIV1,PIV2,PIV3)in children with different years,genders,ages,months,and diseases was compared.Results 1676 cases of virus were detected in 6880 hospitalized children,accounting for 24.36%(1676/6880).The number of virus detection cases from high to low was:RSV 834 cases(12.12%),ADV 222 cases(3.23%),IFA 217 cases(3.15%),PIV3184 cases(2.67%),IFB 122 cases(1.77%),PIV175 cases(1.09%),PIV222 cases(0.32%).The annual virus detection rate from low to high was:18.67%(256/1371)in 2015,21.12%(323/1529)in 2016,25.84%(379/1467)in 2017,and 26.91%(360/1338),30.47%in 2019(358/1175).The difference in the detection rate of different viruses in the same year was statistically significant(P<0.05);except for RSV and PIV1,the difference in the detection rate of the same virus in different years was statistically significant(P<0.05).The detection rate of RSV in each year was higher than that of the other six viruses,and the difference was statistically significant(P<0.05);IFB had the largest number of detected cases in 2016,IFA had the largest number of detected cases in 2017,and ADV and PIV3 had the largest number of detected cases in 2019.There were 1

关 键 词：儿童 呼吸道感染 呼吸道病毒 病原学分析 

分 类 号：R725.6[医药卫生—儿科]