某传染病医院住院患者多重耐药菌感染的监测情况及影响因素分析  

Surveillance status and influencing factors of multidrug-resistant organism an infection in inpatients in an infectious disease hospital

作　　者：班立芳 李轶[2] 孔庆飞[1] 赵鲜丽 李小龙[1] BAN Li-fang;LI Yi;KONG Qing-fei;ZHAO Xian-li;LI Xiao-long(The Sixth People's Hospital of Zhengzhou,Zhengzhou Henan 450015;Henan Provincial People's Hospital,China)

机构地区：[1]郑州市第六人民医院,河南郑州450015 [2]河南省人民医院

出　　处：《中国消毒学杂志》2020年第12期925-927,共3页Chinese Journal of Disinfection

基　　金：河南省医学科技攻关计划项目(SBGJ2018084)。

摘　　要：目的对医院临床科室多重耐药菌(MDRO)的感染情况调查,并分析其影响因素。方法采用回顾性调查方法对医院2018年1-12月发生MDRO感染的491例住院患者进行调查,分析发生MDRO感染的危险因素。结果MDRO感染以大肠埃希菌、鲍曼不动杆菌和金黄色葡萄球菌为主;MDRO感染发生较高的科室为ICU、感染科(艾滋病病区)和神经外科;MDRO感染组患者年龄≥60岁、抗菌药使用种类≥3类、有基础疾病、住院时间≥10 d,以及有侵入性操作的占比均高于非MDRO感染组,差异有统计学意义(P<0.05);Logistic回归分析发现抗菌药使用种类、住院时间和侵入性操作是MDRO感染的危险因素(P<0.05)。结论传染病医院MDRO感染的发生以ICU、感染科(艾滋病病区)和神经外科为主,其危险因素主要为抗菌药使用种类、住院时间和侵入性操作,在临床治疗和护理中,应对重点科室和危险因素进行针对性的管理。Objective To investigate the infection situation of multidrug-resistant organism(MDRO)infection in hospital clinical departments and analyze the influencing factors.Methods 491 hospitalized patients with MDRO infection in the hospital from January 2018 to December 2018 were monitored for infection,and the risk factors were analyzed.Results The major pathogens of MDRO infection were Escherichia coli,Acinetobacter baumannii and Staphylococcus aureus.The departments with high incidence of MDRO infections were ICU,infectious disease department(AIDS area)and neurosurgery.The proportions of patients in the MDRO infection group who were≥60 years old,the types of antibiotics used≥3,underlying diseases,length of stay≥10 d and invasive operation were higher than those in non-MDRO infection group(P<0.05).Multivariate Logistic regression analysis showed that the types of antibiotics used,length of stay and invasive operation were risk factors for MDRO infection(P<0.05).Conclusion The major departments of MDRO infections are ICU,infectious disease department(AIDS area)and neurosurgery in infectious disease hospital.The main risk factors are the types of antibiotics used,length of stay and invasive operation.In clinical treatment and care,the risk factors and key departments should be given targeted management.

关 键 词：多重耐药菌 感染 监测 影响因素 

分 类 号：R378[医药卫生—病原生物学] R197.323[医药卫生—基础医学]