多囊卵巢综合征与自身免疫性甲状腺病相关性研究进展  

Research progress in the correlation between polycystic ovary syndrome and autoimmune thyroid disease

作　　者：金晓慧 李静[1] JIN Xiao-hui;LI Jing(Department of Endocrinology and Metabolism,the First Hospital of China Medical University,Shenyang 110001,China)

机构地区：[1]中国医科大学附属第一医院内分泌科,辽宁沈阳110001

出　　处：《中国实用内科杂志》2021年第1期35-39,共5页Chinese Journal of Practical Internal Medicine

基　　金：国家重点研发计划(2017YFC0907403);国家科技部精雅医研究重点专项(2017YF0907403);国家自然科学基金面上项目(81771741);辽宁省教育厅第四批辽宁特聘教授人才项目(辽教发2014-187号)。

摘　　要：多囊卵巢综合征(PCOS)和自身免疫性甲状腺病(AITD)都是常见的内分泌疾病,都可以对人体健康带来严重的影响。越来越多的研究证实,PCOS患者易合并AITD,而AITD的发生也对女性的生殖功能有一定影响。虽然2种疾病的发病机制目前还不是十分明确,但遗传因素、自身免疫、胰岛素抵抗、相关激素异常、维生素D缺乏和肠道菌群失调等均可能起到一定作用。文章将对PCOS和AITD的相关性做一阐述。Polycystic ovary syndrome(PCOS)and autoimmune thyroid disease(AITD)are common endocrine diseases,which can have serious effects on human health.More and more studies have confirmed that patients with PCOS are prone to have AITD,and AITD also has a certain impact on female reproductive function.Although the pathogenesis of the two diseases is not very clear,genetic factors,autoimmunity,insulin resistance,related hormone abnormalities,vitamin D deficiency and intestinal flora may play a role.This article will review the correlation between PCOS and AITD.

关 键 词：多囊卵巢综合征 自身免疫性甲状腺病 胰岛素抵抗 自身免疫 

分 类 号：R588.6[医药卫生—内分泌]