高危老年股骨粗隆间骨折外固定架固定术后凝血功能与年龄的相关性研究  

Relationship between coagulation function and age after external fixator of femoral intertrochanteric fractures in high-risk elderly patients

作　　者：杨名帅 田雅峰 李云峰[2] 薛鹏宇 朱艳风 董少阳 张毅立 陈宝生 田野 YANG Ming-shuai;TIAN Ya-feng;LI Yun-feng;XUE Peng-yu;ZHU Yan-feng;DONG Shao-yang;ZHANG Yi-li;CHEN Bao-sheng;TIAN Ye(Department of Orthopaedic,Affiliated Hospital of Hebei University of Chinese Medicine,Shijiazhuang,Hebei 050011,China)

机构地区：[1]河北省中医院(河北中医学院附属医院)骨伤一科,河北石家庄050011 [2]河北中医学院生化教研室 [3]河北中医学院研究生学院

出　　处：《中国骨与关节损伤杂志》2021年第2期118-122,共5页Chinese Journal of Bone and Joint Injury

基　　金：河北省科技计划项目(152777228)。

摘　　要：目的探讨高危老年股骨粗隆间骨折组合式外固定架固定术后患者凝血功能与年龄的相关性,为临床预防与治疗此类患者术后深静脉血栓提供参考。方法纳入自2014-01—2019-12采用组合式外固定架固定手术治疗的80例高危老年股骨粗隆间骨折,60岁组20例,70岁组23例,80岁组25例,90岁组12例。比较各组术后(第3、7、14天)D-二聚体、凝血酶原时间、活化部分凝血活酶时间、凝血酶时间、纤维蛋白原。结果 4组术后深静脉血栓发生率差异无统计学意义(P>0.05)。4组术后第3、7、14天D-二聚体、凝血酶原时间、活化部分凝血活酶时间、凝血酶时间、纤维蛋白原差异无统计学意义(P>0.05)。高危老年股骨粗隆间骨折外固定架固定手术前后患者年龄与D-二聚体水平、凝血功能指标的相关性较小。结论高危老年股骨粗隆间骨折适合采用组合式外固定架固定治疗,术后患者的D-二聚体水平、凝血功能不受年龄影响而改变,而且术后深静脉血栓形成风险低。ObjectiveTo explore the correlation between coagulation function and age in high-risk elderly patients with femoral intertrochanteric fractures after combined external fixator fixator,so as to provide reference for clinical prevention and treatment of postoperative deep venous thrombosis in such patients.MethodsEighty high-risk elderly patients with femoral intertrochanteric fractures were treated with combined external fixator from January 2014 to December 2019,including 20 cases in 60-year-old group,23 cases in 70-year-old group,25 cases in 80-year-old group and 12 cases in 90-year-old group.D-dimer,prothrombin time,activated partial thromboplastin time,thrombin time and fibrinogen were compared in each group on the 3rd,7th and 14th day after operation.ResultsThere was no significant difference in the incidence of postoperative deep venous thrombosis among the four groups(P>0.05).There was no significant difference in D-dimer,prothrombin time,activated partial thromboplastin time,thrombin time and fibrinogen among the four groups on the 3rd,7th and 14th day after operation(P>0.05).In the high-risk elderly patients with femoral intertrochanteric fractures,there was little correlation between the age of the patients and the level of D-dimer and the index of blood coagulation before and after external fixator fixation.ConclusionHigh-risk elderly patients with femoral intertrochanteric fractures are suitable for the treatment of combined external fixator,the postoperative D-dimer and blood coagulation function are not affected by age,and the risk of postoperative deep venous thrombosis is low.

关 键 词：股骨粗隆间骨折 老年高危患者 组合式外固定架 年龄 凝血功能 D-二聚体 

分 类 号：R687.3[医药卫生—骨科学]