器官移植供体感染状态评估研究进展  

Research progress on of infection status evaluation of organ transplant donors

作　　者：徐智高[1] 薛承彪[1] 熊艳[1] 罗凯锋 叶啟发[1,2] 代永安[1] 田德英 朱有华[4] XU Zhigao;XUE Chengbiao;XIONG Yan;LUO Kaifeng;YE Qifa;DAI Yong'an;TIAN Deying;ZHU Youhua(Zhongnan Hospital of Wuhan University,Institute of Hepatobiliary Diseases of Wuhan University,Transplant Center of Wuhan University&Hubei Key Laboratory of Medical Technology on Transplantation,Wuhan 430071,Hubei,China;The 3rd Xiangya Hospital of Central South University,Research Center of National Health Ministry on Transplantation Medicine Engineering and Technology,Changsha 410013,Hunan,China;Tongji Hospital,Tongji Medical College ofHuazhong University of Science and Technology,Wuhan 430030,Hubei,China;Transplantation Center,Shanghai Changzheng Hospital,Shanghai 200003,China)

机构地区：[1]武汉大学中南医院/武汉大学肝胆疾病研究院/武汉大学医学移植中心/移植医学技术湖北省重点实验室,湖北武汉430071 [2]中南大学湘雅三医院/卫生部移植医学工程技术研究中心,湖南长沙410013 [3]华中科技大学同济医学院附属同济医院,湖北武汉430030 [4]上海长征医院器官移植中心,上海200003

出　　处：《武汉大学学报（医学版）》2021年第2期193-198,共6页Medical Journal of Wuhan University

摘　　要：2020年初,新型冠状病毒肺炎在全球范围内暴发,器官移植供体感染评估标准也应随之发生改变,因此,有必要对器官移植关于供体质量的感染评估标准进行更新。供体器官捐献的绝对禁忌证的感染病原谱有增加,供体质量的感染评估程序也发生了相应变化。建立供体器官受者的系统化监测体系是精准化治疗的基础,通过高危感染供体弃与用的选择、尽早发现及正确诊断及时采用恰当的防治措施,有望使供体来源感染的发生率及危害性大幅度降低。本文通过分类分析供体来源的感染,并针对不同病原体感染的供体所做的处理措施进行归纳,对供体的感染质量评估标准和评估流程进行综述。In early 2020, the outbreak of new coronavirus pneumonia broke out globally, and the assessment criteria for organ transplant donor infections also brought new changes. Under the situation of the new crown epidemic, it is necessary to update the infection assessment criteria for organ transplantation with regard to donor quality. The infectious pathogen spectrum of the absolute contraindications of donor organ donation has been updated, and the procedures for evaluating donor quality infections have changed accordingly. This review analyzes the infections from the donors by classification, and summarizes the treatment measures taken by the donors infected by different pathogens, and summarizes the evaluation standards and evaluation procedures of the donors′ infection quality.

关 键 词：器官移植供体 感染 器官捐献 

分 类 号：R617[医药卫生—外科学]