高龄老年人肌少症与膳食摄入的相关性研究  

The correlation between sarcopenia and energy intake in people of advanced age

作　　者：任姗姗[1] 李冠臻[1] 汪明芳[1] 王丽娟[1] 杨子艳 Ren Shanshan;Li Guanzhen;Wang Mingfang;Wang Lijuan;Yang Ziyan(Department of Nutrition,Beijing Hospital,National Center of Gerontology,Institute of Geriatric Medicine,Chinese Academy of Medical Sciences,Beijing 100730,China)

机构地区：[1]北京医院营养科国家老年医学中心中国医学科学院老年医学研究院,100730

出　　处：《中华老年医学杂志》2021年第2期212-215,共4页Chinese Journal of Geriatrics

摘　　要：目的分析高龄老年人肌少症发生的相关影响因素,为高龄老年人肌少症防治提供思路和依据。方法回顾分析,入选2014年12月至2017年7月就诊于北京医院营养科的高龄老年人167例根据2014年亚洲少肌症工作组肌少症诊断标准分为肌少症组(46例,27.5%)与非肌少症组(121例),分析不同性别患者身体成分与膳食摄入能量及三大营养素量和比例的差异,采用多元线性回归的方法分析与高龄肌少症发生相关的影响因素。结果与高龄非肌少症组比较,高龄肌少症患者体质指数、腰臀比、脂肪量、饮食摄入总能量、蛋白质较低(均P<0.05),年龄及脂肪摄入量较高(均P<0.05);高龄老年人中,女性的左手和右手握力、骨骼肌量、骨骼肌指数、矫正体质指数的骨骼肌量、肌酐、饮食摄入总能量、碳水化合物、脂肪及蛋白质低于男性(均P<0.05),体脂百分比高于男性(P<0.05)。多元Logistic回归结果显示,高龄患者肌少症发生与蛋白摄入不足(β=-0.290,OR=0.748,95%CI:0.569~0.984,P<0.05)和脂肪量减少(β=-2.673,OR=0.069,95%CI:0.010~0.488,P<0.05),而内脏脂肪偏多(β=0.739,OR=2.094,95%CI:1.219~3.597,P<0.01)有关。结论高龄老年人肌少症发生率较高,与蛋白摄入不足、脂肪分布异常有关。对高龄肌少症患者应及早进行个体化的营养评价及支持。Objective To analyze influencing factors for sarcopenia in people of advanced age,in order to provide insight and evidence for the prevention and treatment of sarcopenia in people belonging to this age group.Methods Data from 167 people of advanced age seeking care at our department from December 2014 to July 2017 were retrospectively analyzed.According to the diagnostic criteria for sarcopenia of the Asian Working Group for Sarcopenia,subjects were divided into the sarcopenia group(n=46,27.5%)and the non-sarcopenia group(n=121).Differences in body composition,energy intake,quantities and proportions of three major nutrients were analyzed between males and females.Related influencing factors for sarcopenia were analyzed by using multiple linear regression.Results Compared with the non-sarcopenia group,the sarcopenia group had lower body mass index,waist-hip ratio,fat mass,total energy intake and protein(P<0.05)but higher age and fat intake(P<0.05).Values for grip strength,muscle mass,index of skeletal muscle,adjusted muscle mass by body mass index,total energy intake,carbohydrates,fat and protein were lower and the percentage of body fat was higher in females than in males(P<0.05).Multiple Logistic regression analysis showed that insufficient intake of protein(β=-0.290,OR=0.748,95%CI:0.569-0.984,P<0.05),reduction of body fat mass(β=-2.673,OR=0.069,95%CI:0.010-0.488,P<0.05)and excessive visceral fat accumulation(β=0.739,OR=2.094,95%CI:1.219-3.597,P<0.01)were correlated with sarcopenia in people of advanced age.Conclusions The occurrence of sarcopenia is higher in people of advanced age and is related to insufficient intake of protein,reduction of body fat mass and excessive visceral fat accumulation.Individualized nutrition evaluation and support should be carried out as early as possible for people in this age group.

关 键 词：老年人 80以上 肌少症 蛋白质 脂肪 

分 类 号：R685[医药卫生—骨科学]