苦皮藤中两个新的β-二氢沉香呋喃型化合物的NMR数据解析  

An NMR Study on Two New β-Dihydroagrofuran Compounds in Celastrus angulatus Maxim

作　　者：廖怀玉 韩红园 陈飞[2] 张海艳[2] 杨静[1] 赵天增[2] LIAO Huai-yu;HAN Hong-yuan;CHEN Fei;ZHANG Hai-yan;YANG Jing;ZHAO Tian-zeng(Henan University of Traditional Chinese Medicine,Zhengzhou 450046,China;Key Laboratory of Natural Products,Henan Academy of Science,Zhengzhou 450002,China)

机构地区：[1]河南中医药大学,河南郑州450046 [2]河南省科学院天然产物重点实验室,河南郑州450002

出　　处：《波谱学杂志》2021年第1期101-109,共9页Chinese Journal of Magnetic Resonance

基　　金：“重大新药创制”科技重大专项(2018ZX09711001-008-004).

摘　　要：从南蛇藤属植物苦皮藤中分离出两个新的β-二氢沉香呋喃型化合物:1β,2β,15-三乙酰氧基-8α-(α-甲基)-丁酰氧基-9β-苯甲酰氧基-4α,6α-二羟基-β-二氢沉香呋喃(化合物Ⅰ)和1β,15-二乙酰氧基-8α-(α-甲基)-丙酰氧基-2β,9β-二苯甲酰氧基-4α,6α-二羟基-β-二氢沉香呋喃(化合物Ⅱ).通过核磁共振(NMR,包括^(1)H NMR、^(13)C NMR、DEPT、^(1)H-^(1)H COSY、NOESY、HSQC、HMBC)技术对化合物所有的^(1)H和^(13)C NMR信号进行了全归属和详细解析.Two new β-dihydroagrofuran compounds,1β,2β,15-triacetoxy-8α-(α-methyl)-butanoyloy-9β-benzoxy-4α,6α-dihydroxy-β-dihydroagrofuran(compound Ⅰ)and 1β,15-diacetoxy-8α-(α-methyl)-propionyloxy-2β,9β-dibenzoxy-4α,6α-dihydroxy-β-dihydroagrofuran(compound Ⅱ),were isolated from Celastrus angulatus Maxim.The chemical shifts of the two new compounds were assigned by one-and two-dimensional nuclear magnetic resonance(NMR)techniques.Their structures were elucidated.

关 键 词：核磁共振(NMR) 南蛇藤属 β-二氢沉香呋喃 苦皮藤 

分 类 号：O482.53[理学—固体物理]