特应性皮炎与精神神经因素相互作用的研究进展  

Research progress on the interaction between atopic dermatitis and neuropsychiatric factors

作　　者：林薇[1] 周琼艳[2] 黄静[1] 赵可喻 许素玲[2] LIN Wei;ZHOU Qiongyan;HUANG Jing;ZHAO Keyu;XU Suling(Department of Pharmacy,the Affiliated Hospital of Medical School,Ningbo University,Zhejiang,Ningbo 315020,China;Department of Dermatology,the Affiliated Hospital of Medical School,Ningbo University,Zhejiang,Ningbo 315020,China;Ningbo University of Medical School,Zhejiang Province,Ningbo 315000,China)

机构地区：[1]宁波大学医学院附属医院药剂科,浙江宁波315020 [2]宁波大学医学院附属医院皮肤科,浙江宁波315020 [3]宁波大学医学院,浙江宁波315000

出　　处：《中国医药导报》2021年第5期33-36,共4页China Medical Herald

基　　金：浙江省公益技术研究计划项目(LGD19H110001);浙江省实验动物科技计划项目(2018C37101);浙江省自然科学基金项目(LY18H110003);浙江省医药卫生重大科技计划项目(WKJ-ZJ-2012)。

摘　　要：特应性皮炎(AD)是一种慢性炎症性皮肤病,以湿疹样皮疹、皮肤干燥和严重瘙痒为主要特点。AD会影响患者的心理健康,严重者可出现焦虑、抑郁等情绪异常,甚至自杀。长期精神压力大或有焦虑、抑郁等精神神经疾病,也可能会诱发或加重AD。本文综述AD相关的精神症状以及精神神经疾病对AD的影响,并讨论了两者之间相互影响的可能机制。AD和精神神经因素之间可能形成恶性循环,因此,AD诊治过程中医生应重视精神神经疾病的筛查并及时干预。Atopic dermatitis(AD)is a chronic inflammatory skin disease characterized by eczema-like rash,dry skin,and severe itching.AD can affect the mental health of patients.In severe cases,emotional abnormalities such as anxiety and depression can occur,and even suicide.Long-term mental stress or anxiety,depression and other neurological diseases may also induce or aggravate AD.This article reviews AD-related psychiatric symptoms and the influence of neuropsychiatric diseases on AD,and discusses the possible mechanisms of the interaction between the them.A vicious circle may be formed between AD and neuropsychiatric factors.Therefore,doctors should pay attention to the screening of neuropsychiatric diseases and intervene in time during the diagnosis and treatment of AD.

关 键 词：特应性皮炎 精神神经因素 焦虑 抑郁 相互作用 

分 类 号：R758.2[医药卫生—皮肤病学与性病学]