住院老年细菌性肺炎多重耐药菌感染的临床分析  

Clinical Analysis of Multidrug-resistant Bacterial Infection in Hospitalized Elderly Patients with Bacterial Pneumonia

作　　者：王元宝 刘莉娜[1] 顾俊文 龙丹 WANG Yuanbao;LIU Lina;GU Junwen;LONG Dan(Changji Branch of First Affiliated Hospital of Xinjiang Medical University,Changji,Xinjiang 831100,China;General Hospital of Sixth Division of Xinjiang Corps,Wujiaqu,Xinjiang 831300,China)

机构地区：[1]新疆医科大学第一附属医院昌吉分院,新疆昌吉831100 [2]新疆兵团第六师总医院,新疆五家渠831300

出　　处：《大医生》2020年第22期108-110,共3页Doctor

摘　　要：目的分析住院老年细菌性肺炎患者的多重耐药菌感染的临床特征。方法选取新疆医科大学第一附属医院昌吉分院2018年4月至2020年7月446例老年细菌性肺炎患者,对老年细菌性肺炎多重耐药性细菌感染患者(观察组251例)与非多重耐药性细菌感染患者(对照组195例)的临床特点与病原学特征进行分析。结果观察组抗生素调整率高于对照组,而治疗有效率低于对照组,且观察组住院时间长于对照组(P<0.05);两组患者临床表现与炎症指标比较差异无统计学意义(P>0.05);常见病原菌为鲍曼不动杆菌(AB菌)(25.78%)、铜绿假单胞菌(29.37%)、嗜麦芽窄食单胞菌(7.40%)、洋葱伯克霍尔德菌(5.83%)、金黄色葡萄球菌(10.31%)、大肠埃希菌(6.73%)、肺炎克雷伯杆菌(3.81%)、屎肠球菌(1.12%)。结论老年细菌性肺炎多重耐药菌感染发生率高,临床上需高度警惕,对多重耐药菌感染进行准确评估,并给予针对性治疗。Objective To analyze the clinical characteristics of multidrug resistant bacteria infection in hospitalized elderly patients with bacterial pneumonia.Methods Totally 446 elderly patients with bacterial pneumonia from April 2018 to July 2020 in Changji Branch of First Affiliated Hospital of Xinjiang Medical University were selected,and then divided into the elderly patients with bacterial pneumonia multidrug-resistance(observation group 251)and non multidrug-resistant patients(control group 195).The clinical and pathogenic characteristics of the patients were compared.Results The antibiotic adjustment rate of the observation group was higher than that of the control group,while the effective rate of treatment was lower than that of the control group,and the observation group was hospitalized longer than the control group(P<0.05);There was no statistically significant difference between the clinical manifestations and inflammatory indexes of the patients in the group(P>0.05);common pathogens were Acinetobacter baumannii(AB bacteria)(25.78%),Pseudomonas aeruginosa(29.37%),and Stenomonas maltophilia(7.40%),Burkholderia cepacia(5.83%),Staphylococcus aureus(10.31%),Escherichia coli(6.73%),Klebsiella pneumoniae(3.81%),feces Cocci(1.12%).Conclusion Bacterial pneumonia in the elderly has a high incidence of multidrug-resistant bacteria infection.It is necessary to be highly vigilant in clinical practice,accurately evaluate multidrug-resistant bacteria infection,and give targeted treatment.

关 键 词：老年患者 细菌性肺炎 多重耐药菌 住院感染 

分 类 号：R44[医药卫生—诊断学]