不同CD4水平艾滋病患者发生机会性感染的临床分析  

Analysis of opportunistic infections in patients with AIDS at different CD4 levels

作　　者：游春芳[1] 唐娟[1] 周利民[1] 邓薇[1] 唐静[1] 王雪容[1] You Chunfang;Tang Juan;Zhou Limin;Deng Wei;Tang Jing;Wang Xuerong(Department of Infectious Diseases,the First Peoples Hospital of Zigong,Zigong 643000,China)

机构地区：[1]四川省自贡市第一人民医院感染科,643000

出　　处：《临床医学》2021年第1期1-3,共3页Clinical Medicine

基　　金：2018年自贡市卫生计生委重点项目(2018CZ03)。

摘　　要：目的比较不同CD4^(+)T淋巴细胞(简称CD4+细胞)水平艾滋病患者发生机会性感染的情况。方法将2018年1月至2019年7月自贡市第一人民医院收治的145例住院艾滋病患者分为A组(CD4^(+)≤100/μl)、B组(100/μl 200/μl)。比较各组患者发生的机会性感染的情况。结果A组机会性感染发生率最高(95.00%,76/80),C组最低(51.85%,14/27),B组为86.84%(33/38),差异有统计学意义(P<0.05)。耶氏肺孢子菌肺炎发生率三组比较差异有统计学意义(P<0.05);细菌性肺炎、口腔真菌病、真菌性肺炎发生率A组高于C组,差异有统计学意义(P<0.05)。结论CD4^(+)细胞数越低,机会性感染率越高,及时、适时的抗病毒治疗尤为重要。Objective To compare the opportunistic infection rates of AIDS patients with different levels of CD4^(+)T lymphocytes(referred to as CD4+cells).Methods A total of 145 inpatients with AIDS were divided into three groups:group A(CD4+≤100/μl),group B(100/μl<CD4^(+)≤200/μl),group C(CD4^(+)>200/μl).The opportunistic infection rates were compared in each group.Results The incidence of opportunistic infection among the three groups was highest in group A(95.00%,76/80),lowest in group C(51.85%,14/27)and 86.84%(33/38)in group B(P<0.05).The incidence of PCP was significantly different among the three groups(P<0.05).The incidences of Bacterial pneumonia,oral mycosis and fungal pneumonia were higher in group A than those in group C,with significant differences(P<0.05).Conclusions The lower the number of CD4+cells,the higher the opportunistic infection rate.Timely and appropriate antiviral treatment is particularly important.

关 键 词：艾滋病 CD4^(+)T淋巴细胞 机会性感染 

分 类 号：R512.91[医药卫生—内科学]