人腺病毒分子生物学分型检测方法的研究进展  

Research progress on molecular biological techniques for human adenovirus detection

作　　者：王瑞欢 陈丽丽[2] 马学军[3] 张红[1] WANG Rui-huan;CHEN Li-li;MA Xue-jun;ZHANG Hong(Hunan Provincial Centerfor Disease Control and Prevention,Changsha,Hunan 410005,China;School of Public Health,University of South Chinat Hengyangi Hunan 421001,China;NHC Key Laboratory of Medical Virology and Viral Diseases,National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China)

机构地区：[1]湖南省疾病预防控制中心,湖南长沙410005 [2]南华大学公共卫生学院,湖南衡阳421001 [3]中国疾病预防控制中心病毒病预防控制所,国家卫生健康委员会医学病毒和病毒病重点实验室,北京102206

出　　处：《实用预防医学》2021年第3期382-384,F0003,共4页Practical Preventive Medicine

基　　金：十三五重大项目(2018ZX10711001,2017ZX10104001和2018ZX10713-002);湖南省重点研发计划(2017SK2101)。

摘　　要：人腺病毒(human adenovirus,HAdV)是引起呼吸道感染的常见病原体,不同型别的组织嗜性不同,由其感染所引起疾病的严重程度也不同。该病毒的感染所致疾病仅靠临床表现很难确定病毒的类型,因此,HAdV的分型鉴定对其所引起疾病的诊断与治疗具有较大的帮助,本文综述了用于该病毒分型检测的分子生物学手段,具有一定的临床意义。Human adenovirus(HAdV)is the main pathogen causing respiratory infections.Different serotypes have different tissue tropisms,and the severity of the disease caused by them is also different.It is difficult to determine the serotype of HAdV based only on the clinical manifestations of the disease caused by the virus;and hence,serotyping of HAdV is of great help to diagnosis and treatment of the disease.This paper summarizes the molecular biological detection technique and serotyping methods of HAdV,which have certain clinical significance.

关 键 词：人腺病毒 分子生物学 分型 

分 类 号：R373[医药卫生—病原生物学]