Essential Oils of Lavandula stoechas subsp.luisieri as Antifungal Agent against Fungi from Strawberry Tree Fruit  

作　　者：Joana Domingues Fernanda Delgado JoséCarlos Gonçalves Cristina Santos Pintado 

机构地区：[1]CBPBI-Plant Biotechnology Centre of Beira Interior,Quinta da Senhora de Mércules,Apartado 119,6001-909,Castelo Branco,Portugal [2]CICS-UBI-Health Sciences Research Centre,Universidade da Beira Interior,Av.Infante D.Henrique 6200-506,Covilhã,Portugal [3]IPCB-ESA-Instituto Politécnico de Castelo Branco,Escola Superior Agrária,Quinta da Senhora de Mércules,Apartado 119,6001-909,Castelo Branco,Portugal [4]CERNAS-IPCB-Research Centre for Natural Resources,Environment and Society,Instituto Politécnico de Castelo Branco,Portugal

出　　处：《Journal of Pharmacy and Pharmacology》2021年第3期98-106,共9页药剂与药理学（英文版）

基　　金：CENTRO 2020,PROVERE-Operational Program CENTRO-04-3928-FEDER-000009,Strawberry TreeInnovation Platform Action,Portugal 2020 and European Union by FEDER and by COOP4PAM-Cooperar para crescer no setor das plantas aromáticas e medicinais-Projeto INTERREG/Programa Espanha-Portugal(POCTEP),0665_COOP4PAM_4_P.

摘　　要：L.stoechas subsp.luisieri is one of the five spontaneous species of the genus Lavandula that occurs spontaneously in Portugal.The chemical profile and antifungal activity of L.stoechas subsp.luisieri essential oils were investigated.The essential oil of two phenological stages was isolated by hydrodistillation and their chemical components analyzed by GC-FID/GC-MS.The minimum inhibitory concentration(MIC)and the minimum fungicidal concentration(MFC)of both essential oils were determinate to verify antifungal activity against different strains of fungi isolated from strawberry tree.The fungi tested were Aspergillus carbonarius,Rhizopus stolonifer,Penicillium brevicompactum,Aureobasidium pullulans and Saccothecium rubi.Essential oils were characterized by a high percentage of oxygenated monoterpenes(46-64%)such as trans-α-necrodyl acetate(12.58%),fenchone(5.97%),1,8-cineole(4.84%)and 5-methylene-2,3,4,4-tetramethylcyclopenten-2-enone(10.97%)were the major compounds in essential oil from dormancy stage,while the main compounds in flowering stage were trans-α-necrodyl acetate(26.90%),trans-α-necrodol(13.02%),lavandulyl acetate(6.53%)and linalool(5.82%).A strong antifungal activity of the essential oils was found against all strains,with MIC and MFC values ranged from 0.07-0.29μL/mL and 0.58-9.33μL/mL,respectively.

关 键 词：Portuguese short-stalked lavender HYDRODISTILLATION Gas Chromatography Chemical characterization Minimum inhibitory concentration Minimum fungicidal concentration. 

分 类 号：O62[理学—有机化学]