三种MRI生理学定量技术对早期膝关节软骨损伤的诊断价值  

Diagnostic value of three MRI physiological quantitative techniques for early cartilage injury of knee joint

作　　者：朱莉 邹文远[2,3] 敖锋[2,3] ZHU Li;ZOU Wenyuan;AO Feng(Postgraduate Training Base,Hubei University of Medicine,Jinzhou Medical University,Shiyan 442000,China)

机构地区：[1]锦州医科大学湖北医药学院研究生培养基地,湖北十堰442000 [2]十堰市人民医院放射影像中心,湖北十堰442000 [3]十堰市人民医院放射影像研究所,湖北十堰442000

出　　处：《陕西医学杂志》2021年第3期293-296,共4页Shaanxi Medical Journal

基　　金：湖北省卫生健康委员会科研基金资助项目(WJ2019M050)。

摘　　要：目的:比较T1-mapping、T2-mapping、T2~*-mapping三种MRI生理学定量技术在早期膝关节软骨损伤中的诊断价值。方法:纳入52例行关节镜手术的患者,将国际软骨修复协会软骨损伤分级系统(ICRS)分级为0级损伤者作为对照组,将1、2级损伤者作为早期损伤组。所有患者于术前行患侧膝关节T1-mapping、T2-mapping及T2~*-mapping序列及常规序列MRI扫描。采用受试者工作特征(ROC)曲线对三者的诊断效能进行评价。结果:早期损伤组T1、T2、T2~*值均高于对照组(均P<0.05)。ROC曲线分析结果显示,三种技术对早期膝关节软骨损伤均有较高的诊断效能(均P<0.05),曲线下面积(AUC)由高至低依次为T2~*-mapping、T2-mapping、T1-mapping,且T2~*-mapping序列的敏感度优于另外两个序列。结论:磁共振T1-mapping、T2-mapping及T2~*-mapping序列均可用于早期膝关节软骨损伤的定量诊断,其中T2~*-mapping的诊断价值更高。Objective:To campare the diagnostic value of T1-mapping,T2-mapping and T2*-mapping for early cartilage injury of knee joint.Methods:52 patients underwent arthroscopic surgery were included,and those with grade 0 injury in ICRS were classified as the control group,and those with grade 1 and 2 injuries were regarded as the early injury group.All patients underwent T1-mapping,T2-mapping,T2*-mapping and routine MRI of knee joint before surgery.The diagnostic efficacy of the three quantitative techniques was evaluated by ROC curve.Results:The T1,T2 and T2*values of the early injury group were higher t han those of the control group(all P<0.05).ROC curve analysis results showed that the three techniques had high diagnostic efficiency for early cartilage injury of knee joint(all P<0.05),and the AUC from high to low was T2*-mapping,T2-mapping,T1-mapping,and the sensitivity of the T2*-mapping was better than the other two sequences.Conclusion:T1-mapping,T2-mapping and T2*-mapping sequences can be used for the quantitative diagnosis of early cartilage injury of knee joint,and T2*-mapping has a higher diagnostic value.

关 键 词：膝关节 软骨损伤 T1-mapping T2-mapping T2~*-mapping 关节镜 

分 类 号：R684[医药卫生—骨科学]