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作 者:张萍[1] 李聪颖[2] 张福侠[1] ZHANG Ping;LI Cong-ying;ZHANG Fu-xia(Department of Acupuncture and Moxibustion,Dongzhimen Hospital(Tongzhou Branch),Beijing University of Chinese Medicine,Beijing101100,China;Department of Cardiology,Dongzhimen Hospital(Tongzhou Branch),Beijing University of Chinese Medicine,Beijing101100,China)
机构地区:[1]北京中医药大学东直门医院通州院区针灸科,北京101100 [2]北京中医药大学东直门医院通州院区心血管科,北京101100
出 处:《中国当代医药》2021年第7期158-161,共4页China Modern Medicine
基 金:北京市通州区卫生发展科研专项项目(TF-2017-PT-01-64)。
摘 要:目的探讨穴位埋线治疗高脂血症合并肝功能异常的临床效果及优势。方法选取2017年6月~2020年6月于北京中医药大学东直门医院通州院区就诊的78例高脂血症合并肝功能异常患者作为观察对象,采用随机数字表法将其分为观察组和对照组,每组各39例。观察组患者采用穴位埋线法治疗,对照组患者采用口服血脂康胶囊治疗。比较两组患者的疗效、血脂、体重及肝功能指标变化,比较两组患者的不良反应发生情况。结果两组患者的疗效比较,差异无统计学意义(P>0.05)。观察组患者治疗后的血清总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、三酰甘油(TG)、体重、丙氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)均低于本组治疗前,差异有统计学意义(P<0.05)。观察组治疗后的TG、体重、ALT、AST均低于对照组,差异有统计学意义(P<0.05)。观察组患者未发生不良反应。观察组患者的不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论在治疗高脂血症合并肝功能异常患者时,穴位埋线与口服血脂康胶囊都有很好的降脂作用,但穴位埋线在减轻体重、改善肝功能方面优于口服血脂康胶囊,且无不良反应。Objective To investigate the clinical effect and advantages of acupoint catgut embedding in the treatment of hyperlipidemia with abnormal liver function.Methods A total of 78 patients with hyperlipidemia and abnormal liver function who were treated in Dongzhimen Hospital(Tongzhou Branch),Beijing University of Chinese Medicine from June 2017 to June 2020 were selected as the research subjects,and they were divided into observation group(n=39)and control group(n=39)by the random number table method.The observation group was treated with acupoint catgut embedding method,and the control group was treated with oral Xuezhikang Capsules.The efficacy,blood lipid,body weight and liver function indexes of the two groups were compared,and the incidence of adverse reactions in the two groups was compared.Results There was no significant difference in curative effect between the two groups(P>0.05).After treatment,the serum total cholesterol(TC),triacylglycerol(TG),low-density lipoprotein cholesterol(LDL-C),body weight,alanine aminotransferase(ALT),and aspartate aminotransferase(AST)in the observation group were lower than those before treatment,and the differences were statistically significant(P<0.05).The TG,body weight,ALT and AST of the observation group were lower than those of the control group after treatment,and the differences were statistically significant(P<0.05).No adverse reactions occurred in the observation group.The incidence of adverse reactions in observation group was lower than that in the control group,with statistical significance(P<0.05).Conclusion In the treatment of patients with hyperlipidemia and abnormal liver function,acupoint catgut embedding and oral administration of Xuezhikang Capsules have a great lipid-lowering effect.However,acupoint embedding is better than oral administration of Xuezhikang Capsules in weight reduction and liver function improvement,and there is no adverse reaction.
分 类 号:R245.9[医药卫生—针灸推拿学]
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