超重/肥胖对儿童肠套叠空气灌肠复位的预后影响:倾向性评分匹配分析  

Effect of overweight and obesity on the prognosis of intussusception treated by air enema reduction in children:propensity score matching analysis

作　　者：冯伟 苏小霞 邹玉凤 李苗苗[2] 崔华雷[2] FENG Wei;SU Xiao-xia;ZOU Yu-feng;LI Miao-miao;CUI Hua-lei(Graduate School,Tianjin Medical University,Tianjin 300070,China;Department of Minimally Invasive Surgery,Tianjin Children′s Hospital,Tianjin 300074,China)

机构地区：[1]天津医科大学研究生院,天津300070 [2]天津市儿童医院微创外科,天津300134

出　　处：《天津医科大学学报》2021年第2期137-141,共5页Journal of Tianjin Medical University

基　　金：天津市科技计划项目(14RCGFSY00150)。

摘　　要：目的:探讨超重/肥胖对儿童肠套叠空气灌肠复位(AER)预后的影响。方法:回顾性分析342例经AER的肠套叠患儿临床资料,根据体重指数(BMI)将其分为超重/肥胖(BMI百分比≥85%)及非超重/肥胖(BMI百分比<85%)者,进行倾向性评分匹配后,运用单因素和多因素Logistic回归分析总结超重/肥胖对患儿的预后影响。结果:342例患儿经1:1倾向性评分匹配筛选出65例超重/肥胖及65例非超重/肥胖者,两组临床资料的差异无统计学意义(P>0.05)。匹配后分析显示,超重/肥胖(OR=19.483,95%CI:4.527~83.857)、白细胞(OR=1.347,95%CI:1.138~1.594)及血乳酸(OR=6.072,95%CI:2.149~17.151)为患儿AER预后不良的独立危险因素(均P<0.05)。结论:超重/肥胖是儿童肠套叠AER不良预后的独立危险因素。Objective:To investigate the effect of overweight and obesity on the prognosis of intussusception treated by air enema reduction(AER)in children.Methods:A retrospective analysis of the clinical data of 342 children with intussusception traeted by AER was performed.According to body mass index(BMI),they were divided into overweight and obese(BMI percentage≥85%)and non-overweight-and-obese(BMI percentage<85%).After propensity score matching,univariate and multivariate Logistic regression analysis were used to summarize the effects of overweight and obesity on the prognosis of patients.Results:A total of 65 cases of overweight and obesity and 65 cases of non-overweight and obesity were screened out from 342 children with 1:1 propensity score matching,and there was no significant difference in clinical data between the two groups(P>0.05).Analysis after matching showed that overweight and obesity(OR=19.483,95%CI:4.527-83.857),white blood cell count(OR=1.347,95%CI:1.138-1.594)and blood lactate(OR=6.072,95%CI:2.149-17.151)were independent risk factors for poor prognosis of children with AER(all P<0.05).Conclusion:Overweight and obesity are independent risk factors for the poor prognosis of children with intussusception AER.

关 键 词：肠套叠 超重/肥胖 儿童 预后 倾向性评分匹配 

分 类 号：R720.597[医药卫生—急诊医学] R726.5[医药卫生—儿科]