机构地区:[1]海军军医大学第一附属医院烧伤外科,上海200433 [2]解放军海军92694部队医院,大连116085
出 处:《中华损伤与修复杂志(电子版)》2020年第6期465-469,共5页Chinese Journal of Injury Repair and Wound Healing(Electronic Edition)
基 金:国家自然科学基金面上项目(81772125)。
摘 要:目的观察微动力负压技术(micro-dynamic negative pressure wound therapy,MDNPWT)应用于小面积Ⅲ度低热烧伤创面的临床疗效。方法收集2016年1月至2018年5月于海军军医大学第一附属医院烧伤外科门诊就诊的小面积(≤10 cm2)Ⅲ度低热烧伤患者220例。应用MDNPWT治疗的108例患者设为微动力负压组,采用常规治疗的112例患者设为常规治疗组。微动力负压组患者入组后采取持续微动力负压护创敷料换药,而常规治疗组采用传统的外用药物治疗。对比微动力负压组和常规治疗组的创面愈合时间、换药次数、治疗总费用及手术率。对数据行t检验和χ^(2)检验。结果微动力负压组和常规治疗组的创面愈合时间分别为(31.8±3.5)、(48.0±13.9)d,2组比较差异有统计学意义(t=11.75,P<0.05);微动力负压组和常规治疗组的换药次数分别为(6.4±0.7)、(34.2±3.1)次,2组比较差异有统计学意义(t=18.76,P<0.05);微动力负压组和常规治疗组治疗总费用分别为(2807.5±782.6)、(7516.7±238.3)元,2组比较差异有统计学意义(t=18.55,P<0.05);微动力负压组和常规治疗组的手术率分别为0、70.5%,2组比较差异有统计学意义(χ^(2)=118.9,P<0.05)。结论MDNPWT具有缩短创面愈合时间、减少换药次数、节省治疗总费用及降低小面积深度烧伤创面手术率等优点。因此,MDNPWT可以作为小面积Ⅲ度低热烧伤创面治疗安全有效的新方法。Objective To summarize the clinical effect of micro-dynamic negative pressure wound therapy(MDNPWT)on small area full thickness burn wounds caused by low-heat.Methods Clinical data of 220 outpatients with small area full thickness burn wounds caused by low-heat from Jan,2016 to May,2018 in Department of Burns Surgery,First Affiliated Hospital,Naval Medical University were collected.One hundred and eight patients treated with MDNPWT were set as micro-dynamic negative pressure group.One hundred and twelve patients treated with conventional treatment were set as conventional treatment group.MDNPWT wound dressing were used for dressing change in micro-dynamic negative pressure group,while classic wound dressing were used for dressing change in conventional treatment group.Healing time,frequency of dressing change,total costs,surgery rates of the 2 groups were compared.Data were processed with t test and chi-square test.Results The healing time in the micro-dynamic negative pressure group and conventional treatment group were(31.8±3.5),(48.0±13.9)d,the difference was statistically significant(t=11.75,P<0.05).The average times in the micro-dynamic negative pressure group and conventional treatment group were(6.4±0.7),(34.2±3.1)times,the difference was statistically significant(t=18.76,P<0.05).Total costs in the micro-dynamic negative pressure group and conventional treatment group were(2807.5±782.6),(7516.7±238.3)yuan,the difference was statistically significant(t=18.55,P<0.05).Surgery rates in the micro-dynamic negative pressure group and conventional treatment group were 0 and 70.5%,the difference was statistically significant(χ^(2)=118.9,P<0.05).Conclusion MDNPWT can be used as a new method to treat full thickness burn wounds caused by low-heat as it shows advantages in shortening wound healing time,saving treatment costs,lowing dressing change frequency and surgery rate.
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