东莞市过敏患者血清过敏原特异性IgE检测及其年龄分布  

Detection and age distribution of serum allergen specific IgE in allergic patients in Dongguan city

作　　者：李文瑞 何月敬 叶敏南 李纯 苏小华 LI Wen-rui;HE Yue-jing;YE Min-nan;LI Chun;SU Xiao-hua(Department of Clinical Laboratory,Affiliated Dongguan Children's Hospital,Guangdong Medical University,Dongguan 523326,China)

机构地区：[1]广东医科大学附属东莞儿童医院检验科,广东东莞523326

出　　处：《广东医科大学学报》2021年第1期77-80,共4页Journal of Guangdong Medical University

摘　　要：目的了解东莞市过敏患者血清过敏原特异性IgE(sIgE)检测结果及年龄分布。方法 2018年10月-2019年10月,我院采用德国Mediwiss过敏原检测仪检测了3 894例过敏患者19种血清过敏原sIgE。结果血清过敏原sIgE阳性率前4位依次为户尘螨、牛奶、鸡蛋白和猫毛皮屑,其中牛奶、户尘螨分别在0~3岁、4岁以上患者中阳性率最高。<18岁患者sIgE阳性率随年龄增大而上升,但>18岁者随年龄增加而下降(P<0.05)。不同年龄组sIgE阳性率之间的差异有统计学意义(P<0.05),其中7~17岁组最高(60.3%),≥66岁组最低(30.6%)。不同性别中sIgE阳性率差异有统计学意义(P<0.01)。结论血清过敏原sIgE分布存在年龄差异,不同年龄组的主要过敏原不同。Objective To study the testing results and age distribution of serum allergen specific IgE(sIgE) in allergic patients in Dongguan city. Methods Between October 2018 and October 2019, sIgE levels of 19 serum allergens in 3 894 allergic cases were determined using Mediwiss allergen detector(Germany). Results The sIgE positive rates of the first four allergens were house dust mite, milk, egg white and feline scurf, of which milk and house dust mite were the highest positivity in 0-3 years and >4 years. The sIgE positivity was increased with incremental ages in <18 years but decreased >18 years(P<0.05). The statistical difference of sIgE positivity was significant among different ages(P<0.05) and between genders(P<0.01), with the top(60.3%) in 7-17 years and nadir(30.6%) in ≥66 years. Conclusion The age distribution of positive rates of serum allergen sIgE is variable. The major allergens are different among age groups.

关 键 词：过敏原 特异性IGE 过敏性疾病 

分 类 号：R446.6[医药卫生—诊断学]