湖北省跨地区血液集中化检测资料回顾性分析  

Centralized blood screening across the regions of Hubei province: a retrospective survey

作　　者：李瑜[1] 周先桃[1] 程文娟[1] 许婷婷[1] 许敬 赵磊[1] LI Yu;ZHOU Xiantao;CHENG Wenjuan;XU Tingting;XU Jing;ZHAO Lei(Wuhan Blood Center,Wuhan 430030,China)

机构地区：[1]武汉血液中心,湖北武汉430030

出　　处：《中国输血杂志》2021年第2期154-157,共4页Chinese Journal of Blood Transfusion

摘　　要：目的对湖北省实施跨地区血液集中化检测的各地区血液质量状况及逐年变化趋势进行系统性回顾分析,探讨采供血机构实施血液标本集中化检测的效果及其优势。方法分析2005~2019年期间湖北省5家开展跨地区集中化检测的采供血机构的血液标本检测资料,统计集中化检测标本量、血液筛查总体合格率、各检测项目的总体不合格率和分年度不合格率及其在各地区间的差异。结果湖北省血液集中化检测的各地区间血液质量存在差异,武汉、鄂州、仙桃、天门、潜江5个地区的血液筛查总体合格率分别为97.1%(2 466 396/2 538 871)、96.5%(85 405/88 547)、95.2%(59 087/62 047)、95.5%(68 920/72 146)、94.7%(34 274/36 188)。5个地区的ALT总体不合格率分别为1.472%(37 374/2 538 871)、2.024%(1 792/88 547)、2.840%(1 762/62 047)、2.476%(1 786/72 146)、3.777%(1 367/36 188),存在地区间差异;5个地区的HBsAg总体不合格率分别为0.587%(14 897/2 538 871)、0.664%(588/88 547)、1.094%(679/62 047)、1.282%(925/72 146)、0.862%(312/36 188),存在地区间差异。2005~2019年期间各地区的ALT不合格率均有随年度下降的趋势。武汉、天门、潜江地区的HBsAg不合格率有随年度下降的趋势,武汉、鄂州、天门地区的抗-HCV不合格率有随年度下降的趋势,武汉地区的抗-TP不合格率有随年度下降的趋势。结论血液集中化检测能够优化检测资源配置,发现采供血环节中的问题,提升血站保障血液安全的能力。采供血机构进一步提高血液集中化检测的程度和范围,找到适合本区域的集中化检测模式是今后需要努力解决的方向。Objective To retrospectively analyse the quality status and annual trend of centralized blood screening across the regions of Hubei province, and discuss the effect and advantages of the application of centralized blood screening across blood establishment.Methods Blood screening results of five blood establishment across Hubei province from 2005 to 2019 were statistically analyzed. The sample size, overall rate of qualified blood donations,overall and annual rate of positive testing items were compared among regions. Results There were differences in blood quality among different regions of Hubei province. In Wuhan, Ezhou, Xiantao, Tianmen and Qianjiang, the overall rate of qualified blood donations was 97.1%(2 466 396/2 538 871), 96.5%(85 405/88 547), 95.2%(59 087/62 047), 95.5%(68 920/72 146) and 94.7%(34 274/36 188), respectively;the overall deferral rate of ALT was 1.472%(37 374/2 538 871), 2.024%(1 792/88 547), 2.840%(1 762/62 047), 2.476%(1 786/72 146) and 3.777%(1 367/36 188),with significant differences across regions;the overall positive rate of HBsAg was 0.587%(14 897/2 538 871), 0.664%(588/88 547), 1.094%(679/62 047), 1.282%(925/72 146) and 0.862%(312/36 188), with significant differences across regions. The deferral rate of ALT showed a downward trend by year in these five regions from 2005 to 2019.An decreasing trend in the seroprevalence of HBV was noticed in Wuhan, Tianmen, and Qianjiang,HCV in Wuhan, Ezhou, and Tianmen,as well as syphilis infections in Wuhan.Conclusion Centralized blood screening can optimize the allocation of testing resources, reveal problems during blood collection and supply and improve the ability to guarantee blood safety. Future efforts are needed to expand the scope of centralized blood screening and seek for a centralized screening mode suitable for local situation.

关 键 词：血液筛查 集中化检测 跨地区 不合格率 

分 类 号：R446.1[医药卫生—诊断学]