噻托溴铵粉雾剂治疗慢性阻塞性肺气肿的有效性及安全性探讨  

Efficacy and safety of tiotropium bromide powder in the treatment of chronic obstructive emphysema

作　　者：蔡兴球[1] 蔡兴红[1] CAI Xing-qiu;CAI Xing-hong(Shanghai Jiao Tong University School of Medicine affiliated Xinhua Hospital Chongming Branch,Shanghai 202150,China)

机构地区：[1]上海交通大学医学院附属新华医院崇明分院,上海202150

出　　处：《中国国境卫生检疫杂志》2020年第S01期105-106,共2页Chinese Journal of Frontier Health and Quarantine

摘　　要：目的探究噻托溴铵粉雾剂治疗慢性阻塞性肺气肿的有效性及安全性。方法选取慢性阻塞性肺气肿患者60例,研究时间为2019年5月-2020年5月,分为参照组(30例)和研究组(30例),参照组实施异丙托溴铵气雾剂治疗,研究组实施噻托溴铵粉雾剂治疗,对比治疗效果。结果对于治疗后呼气峰流速、一秒用力呼气容积,研究组明显更优,P<0.05。研究组治疗有效率高于参照组,P<0.05。研究组不良反应发生率低于参照组,P<0.05。结论慢性阻塞性肺气肿肺患者实施噻托溴铵粉雾剂治疗,有效改善肺功能,消除临床症状,提高治疗有效率,不良反应少,安全性高,具有显著治疗效果。Objective To investigate the efficacy and safety of tiotropium bromide powder in the treatment of chronic obstructive emphysema.Methods A total of 60 patients with chronic obstructive emphysema were selected and studied from May 2019 to May 2020.They were divided into the reference group(30 cases)and the study group(30 cases).The treatment group was treated with ipratropium bromide aerosol,while the study group was treated with tiotropium bromide powder,and the treatment effect was compared.Results The peak expiratory flow rate and forced expiratory volume per second after treatment were significantly better in the study group(P<0.05).The effective rate of the treatment group was higher than that of the control group(P<0.05).The incidence of adverse reactions in the study group was lower than that in the control group(P<0.05).Conclusion Tiotropium bromide powder can effectively improve lung function,eliminate clinical symptoms,improve the effective rate of treatment,less adverse reactions,high safety,and have significant therapeutic effect in patients with chronic obstructive pulmonary emphysema.

关 键 词：慢性阻塞性肺气肿 噻托溴铵粉雾 肺功能 安全性 

分 类 号：R322[医药卫生—人体解剖和组织胚胎学]