2013-2018年西安某医院轮状病毒感染流行病学单中心回顾性研究  

Epidemiology of rotavirus infection in a hospital in Xi′an from 2013 to 2018 single-center retrospective study

作　　者：李芳[1] 李雅丽 王静[1] 王军阳[2] 曾晓艳[1] LI Fang;LI Ya-li;WANG Jing;WANG Jun-yang;ZENG Xiao-yan(Department of Clinical Laboratory,the First Affiliated Hospital,Xi′an Jiaotong University,Xi′an,Shaanxi 710061;Department of Immunology and Pathogenic Biology,Xi′an Jiaotong University Health Science Center,Xi′an,Shaanxi 710061,China)

机构地区：[1]西安交通大学第一附属医院检验科,陕西西安710061 [2]西安交通大学医学部免疫学与病原生物学系,陕西西安710061

出　　处：《热带医学杂志》2020年第12期1614-1616,共3页Journal of Tropical Medicine

基　　金：国家自然科学基金(81201326);陕西省重点研发计划(2017SF-170)。

摘　　要：目的探讨A群轮状病毒(RVA)感染情况,为明确A群轮状病毒感染所致腹泻与患者性别、年龄及季节的相关性。方法选自2013-2018年西安交通大学附属医院门急诊和住院腹泻患者13 091例作为研究对象,进行A群轮状病毒抗原检测并进行统计学分析。结果 13 091例腹泻患者中,RVA感染4 354例,阳性率为33.3%。男性患者RVA阳性率为33.0%,女性患者RVA阳性率为33.5%,差异无统计学意义(P>0.05)。各年龄组均可检出轮状病毒,5岁以下婴幼儿是RVA腹泻的高发人群,占95.5%,且0.5~<2岁年龄组阳性率最高(37.2%),差异有统计学意义(P<0.05)。1月、11-12月是RVA感染的高发期。结论 A群轮状病毒感染与儿童腹泻存在密切关系,婴幼儿是RVA的易感人群,RVA感染无性别差异且高发于秋冬季节。Objective To investigate the infection status of group A rotavirus(RVA) from 2013 to 2018,in order to clarify the correlation between diarrhea caused by RVA infection and gender,age and season of patients in this region.Method From 2013 to 2018,13 091 patients with diarrhea admitted to the outpatient emergency and hospitalization department of our hospital were selected for RVA antigen test and statistically analyzed.Results There were 4 354 cases of RVA infection in 13 091 cases of patients with diarrhea;the positive rate was 33.3%.The positive rate of RVA was 33.0% in male patients and 33.5% in female patients,with no statistically significant difference(P>0.05).Rotavirus was detected in all age groups.Infants under 5 years old were at high risk of RVA diarrhea,accounting for 95.5%,and the positive detection rate was highest in the age group 0.5-<2 years old(37.2%),with statistically significant difference(P<0.05).January,November to December was the high incidence period of RVA infection.Conclusions RVA infection was closely related to diarrhea in children.Infants and young children were susceptible to RVA.RVA infection was common in autumn and winter without gender difference.

关 键 词：A群轮状病毒 腹泻 儿童 

分 类 号：R512.5[医药卫生—内科学]