胎儿脐带缠绕与环境暴露因素的关联  被引量:2

The relationship between fetal umbilical cord entanglement and environmental exposure factors

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作  者:岳和欣 黎小秀[2] 湛永乐 陈云利 石英杰 刘璇[1] 景傲 孟耀涵 吕天琛 曲翌敏 马良坤[3] 满冬梅[4] 江宇[1] YUE He-xin;LI Xiao-xiu;ZHAN Yong-le;CHEN Yun-li;SHI Ying-jie;LIU Xuan;JING Ao;MENG Yao-han;LYU Tian-chen;QU Yi-min;MA Liang-kun;MAN Dong-mei;JIANG Yu(Department of Epidemiology and Biostatistics,School of Population Medicine and Public Health,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China;Department of Pediatrics,Dongguan Maternal and Child Health Care Hospital,Dongguan 523000,China;De partment of Obstetrics and Gynecology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100005,China;Department of Obstetrics,Affiliated Hospital of Jining Medical University,Jining 272000,China)

机构地区:[1]中国医学科学院/北京协和医学院群医学及公共卫生学院流行病与生物统计学系,北京100730 [2]东莞市妇幼保健院儿科,东莞523000 [3]中国医学科学院/北京协和医学院北京协和医院妇产科,北京100005 [4]济宁医学院附属医院产科,济宁272000

出  处:《中华疾病控制杂志》2021年第2期133-137,共5页Chinese Journal of Disease Control & Prevention

基  金:中国医学科学院医学与健康科技创新工程(2019-I2M-2-007)。

摘  要:目的了解中国胎儿脐带缠绕现状及其与环境暴露因素的相关性,为预防和干预脐带缠绕提供科学的指导。方法以中国孕产妇队列研究·协和项目的孕妇为研究对象,在孕早期收集孕妇的一般人口学信息和环境暴露信息,随访获取脐带缠绕相关结局,应用多因素非条件Logistic回归分析模型分析胎儿脐带缠绕的影响因素。结果胎儿脐带缠绕的发生率为9.00%。Logistic回归分析模型分析结果显示:调整混杂因素后,与孕期没有暴露于被动吸烟或噪声的孕妇相比,暴露于被动吸烟(OR=1.199, 95%CI:1.010~1.423,P=0.038)或噪声(OR=1.242, 95%CI:1.002~1.541,P=0.048)的孕妇发生脐带缠绕的风险较高。结论孕妇孕期被动吸烟和接触噪声对胎儿脐带缠绕有影响,应加强孕期教育,减少孕妇孕期被动吸烟和噪声环境暴露。Objective To understand the incidence of fetal umbilical cord entanglement in China and its correlation with environmental exposure factors, so as to provide scientific guidance for prevention and intervention of umbilical cord entanglement. Methods The pregnant women of the Chinese Pregnant Women Cohort Study were selected as the research subjects. The general demographic information and environmental exposure information of pregnant women were collected in the early pregnancy, and the related outcomes of umbilical cord entanglement were obtained by follow-up. Multivariate unconditional Logistic regression analysis model was used to analyze the influencing factors of fetal umbilical cord entanglement. Results The incidence of fetal umbilical cord entanglement was 9.00%. The results of Logistic regression analysis showed that after adjusting for confounding factors, pregnant women exposed to passive smoking(OR=1.199, 95% CI: 1.010-1.423, P=0.038) or noise(OR=1.242, 95% CI: 1.002-1.541, P=0.048) had a higher risk of umbilical cord entanglement than those who were not exposed to passive smoking or noise during pregnancy. Conclusions Passive smoking and exposure to noise during pregnancy can affect fetal umbilical cord entanglement. Education during pregnancy should be strengthened to reduce passive smoking and noise exposure during pregnancy.

关 键 词:孕妇 脐带缠绕 影响因素 

分 类 号:R714.5[医药卫生—妇产科学]

 

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