南京地区儿童门急诊季节性流感的分型和淋巴单核细胞含量比的特征分析  

Analysis of Clinical Characteristics of Seasonal Influenza Type and Lymphatic Mononuclear Cell Content Ratio of Children in Outpatient and Emergency Department in Nanjing Area

作　　者：荣菊 邬薇[1] 张爱青[1] RONG Ju;WU Wei;ZHANG Ai-qing(Department of Pediatrics,the Second Affiliated Hospital of Nanjing Medical University,Nanjing 210003,Jiangsu,China)

机构地区：[1]南京医科大学第二附属医院儿科,江苏南京210003

出　　处：《医学信息》2021年第5期147-150,共4页Journal of Medical Information

摘　　要：目的分析南京医科大学第二附属医院儿童门急诊季节性流感的分型特点和淋巴单核细胞含量比,揭示其流行趋势和临床特点。方法回顾性分析2019年12月30日~2020年1月31日于我院诊断为季节性流感的3个月~14岁儿童的临床资料、流感抗原检测和血象特征,分析不同性别、年龄儿童季节性流感的分型、单核细胞计数、淋巴/单核细胞比。结果共检测流感抗原标本2425例,流感检出率为61.15%;不同性别、年龄患儿各类型流感检出率比较,差异有统计学意义(P<0.05),男性患儿中甲流、乙流检出率分别为28.18%、34.18%,女性患儿为23.97%、34.78%;不同年龄中,5~9岁患儿乙流的检出率最高(35.82%),10~14岁患儿的甲流检出率最高(38.99%);确诊患儿中,甲流患儿的单核细胞计数高于乙流患儿,差异有统计学意义(P<0.05);乙流患儿淋巴/单核细胞比高于甲流患儿,差异有统计学意义(P<0.05);甲流、乙流不同年龄段患儿淋巴/单核细胞比值比较,差异有统计学意义(P<0.05)。结论在流感流行期,不同性别、年龄的患儿易患流感病毒类型不同;另外,淋巴/单核细胞的比值可作为不同年龄段儿童流感诊断的辅助指标。Objective To analyze the typing characteristics and lymph mononuclear cell content ratio of seasonal influenza in children's outpatient and emergency department of the Second Affiliated Hospital of Nanjing Medical University,and reveal its epidemic trend and clinical characteristics.Methods Retrospectively analyze the clinical data,influenza antigen detection and blood characteristics of children 3 months to 14 years old who were diagnosed with seasonal influenza in our hospital from December 30,2019 to January 31,2020.Analyze the types,monocyte counts,and lymph/monocyte ratios of seasonal influenza in children of different genders and ages.Results A total of 2425 influenza antigen specimens were tested,and the detection rate of influenza was 61.15%.The detection rate of various types of influenza in children of different genders and ages was compared,the difference was statistically significant(P<0.05).In male children,the detection rates of influenza A and influenza B were 28.18%and 34.18%,respectively,and those of female children were 23.97%and 34.78%;Among different ages,children aged 5 to 9 had the highest detection rate of influenza B(35.82%),and children aged 10 to 14 had the highest detection rate of influenza A(38.99%);Among the diagnosed children,the monocyte counts of children with influenza A were higher than those of children with influenza B,the difference was statistically significant(P<0.05);The lymph/monocyte ratio in children with influenza B was higher than that in children with influenza A,the difference was statistically significant(P<0.05);There was a statistically significant difference in the ratio of lymph/monocytes in children with influenza A and B at different ages(P<0.05).Conclusion During the influenza epidemic,children of different genders and ages are susceptible to different types of influenza viruses;in addition,the ratio of lymphocytes to monocytes can be used as an auxiliary index for the diagnosis of influenza in children of different ages.

关 键 词：儿童 流感 淋巴/单核细胞比 

分 类 号：R511.7[医药卫生—内科学]