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作 者:黄飞燕 覃秋云 张捷 陈莲 陈世新 喻晓燕 HUANG Feiyan;QIN Qiu-yun;ZHANG Jie;CHEN Lian;CHEN Shi-xin;YU Xiao-yan(Laibin City Maternal and Child Health Hospital,Laibin,Guangxi 546100)
出 处:《中国优生与遗传杂志》2020年第10期1227-1230,共4页Chinese Journal of Birth Health & Heredity
摘 要:目的创建艾滋病母婴阻断管理新模式,为完善艾滋病母婴阻断管理提供依据。方法对HIV抗体检测阳性的孕妇,进行焦虑抑郁检测,选择60例HIV抗体检测阳性并具有焦虑和抑郁症状孕产妇,使用随机平行对照方法抽取30例为实验组,30例为对照组。患者及家属签署自愿参与实验及知情同意书。对照组进行常规产前检查和进行母婴阻断抗病毒药物治疗及健康咨询,实验组在常规母婴阻断治疗及健康咨询基础上进行人文关怀,开展2次沙盘游戏心理干预,同时进行抗病毒药物依从性调查,新生儿重要疾病筛查(先天性心脏病筛查、听力筛查、特殊遗传病筛查),比较两组结果。结果干预前两组焦虑及抑郁评分差异无统计学意义(P>0.05),干预后实验组焦虑及抑郁评分明显低于对照组。实验组干预前后的焦虑和抑郁分值差异均有统计学意义(P<0.01);干预前孕妇的抗病毒药服药依从性比较,差异有统计学意义(P<0.01),干预后服药依从性比较,差异无统计学意义(P>0.05),两组新生儿筛查结果无显著差异;新生儿艾滋病早期核酸检测未发现阳性者。结论艾滋病母婴阻断管理增加开展焦虑与抑郁检测,找出焦虑抑郁患者,对其进行人文关怀及沙盘游戏心理干预,可以改善HIV感染孕妇焦虑及抑郁情绪,提高孕妇抗病毒药服药依从性;提高艾滋病母婴阻断成功率,可以作为艾滋病母婴阻断管理的重要内容。Objective:To establish a new model of HIV mother-to-child block management,and provide the basis for improving the management of HIV mother-to-child block.Methods:The pregnant women with positive HIV antibody test were tested for anxiety and depression.60 pregnant women with positive HIV antibody test and symptoms of anxiety and depression were selected.30 cases were selected as experimental group and 30 cases as control group by random parallel control method.The patients and their family members signed voluntary participation and informed consent.Control group routine prenatal examination and maternal and child block the antiviral drug treatment,and health consultation,the experimental group on the basis of routine maternal and child block treatment and health advice to carry on the humanistic care,to carry out two sand table games psychological intervention,antiviral drug compliance investigation at the same time,the important disease screening for newborn congenital heart disease(special genetic disease screening,hearing screening,screening),compare two sets of results.Results:there was no statistically significant difference in scores of anxiety and depression between the two groups before intervention(P>0.05),and scores of anxiety and depression in the experimental group were significantly lower than those in the control group after intervention.The differences of anxiety and depression scores before and after intervention in the experimental group were statistically significant(P<0.01).Before intervention,there was a statistically significant difference in the compliance of pregnant women with antiviral drugs(P<0.01),but there was no statistically significant difference in the compliance after intervention(P>0.05),and there was no significant difference in the screening results of newborns between the two groups.Neonatal AIDS nucleic acid test did not find positive.Conclusion:The management of MOTHER-to-child block of AIDS can improve the anxiety and depression of hiv-infected pregnant women by increasing
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