荆州地区先天性心脏病新生儿出生情况及母体孕期影响因素分析  

Birth conditions of newborns with congenital heart disease and influencing factors of maternal pregnancy in Jingzhou

作　　者：刘金晶 章琴[2] LIU Jin-jing;ZHANG Qin(Department of Obstetrics and Gynecology,The Second People's Hospital of Jingzhou,Hubei Jingzhou 434000;Department of Obstetrics and Gynecology The First People's Hospital of Jingzhou,Hubei Jingzhou 434000)

机构地区：[1]荆州市第二人民医院妇产科 [2]荆州市第一人民医院妇产科,湖北荆州434000

出　　处：《中国优生与遗传杂志》2020年第10期1244-1247,共4页Chinese Journal of Birth Health & Heredity

摘　　要：目的调查荆州地区先天性心脏病(Congenital heart disease,CHD)新生儿出生情况,并分析其母体孕期影响因素。方法选择荆州地区2018年1月至2019年1月活产的新生儿2265例,收集新生儿及其母亲基本情况,采用彩色多普勒超声心动图筛查CHD患儿,总结该地区CHD新生儿出生情况,并分析其母体孕期影响因素。结果 2265例活产新生儿中有78例患有CHD,其中男38例(48.72%),女40例(51.28%),最常见CHD类型为房间隔缺损合并动脉导管未闭(44.87%),室间隔缺损合并卵圆孔未闭(17.95%);多因素Logistic回归分析结果显示,母亲孕前体质指数偏低及过高、孕次≥3次、糖尿病、阴道出血、近期接触装修、新生儿体重偏低及早产可能是新生儿CHD的独立风险因素,自然受孕可能是独立保护因素。结论荆州地区新生儿CHD发病率较高,危险因素较多,应针对性对怀孕期间不利因素进行综合性干预。Objective:To investigate birth conditions of newborns with congenital heart disease(CHD)in Jingzhou,and to analyze influencing factors of maternal pregnancy.Methods:2265 live birth newborns during the period from January 2018 to January 2019 in Jingzhou were enrolled.The basic conditions of newborns and their mothers were collected.CHD newborns were screened by color Doppler echocardiography.The birth conditions of CHD newborns in the area were summarized.The influencing factors of maternal pregnancy were analyzed.Results:Of the 2265 live birth newborns,there were 78 cases with CHD,including 38 males(48.72%)and 40 females(51.28%).The most common types of CHD were atrial septal defect combined with patent ductus arteriosus(44.87%),and ventricular septal defect combined with patent foramen ovale(17.95%).The results of multivariate Logistic regression analysis showed too low and too high progestational body mass index of mother,number of pregnancy not less than 3 times,diabetes mellitus,vaginal bleeding,recent contacting decoration,too low newborn weight and preterm birth might be independent risk factors for neonatal CHD,while natural conception might be an independent protective factor.Conclusion:The incidence of neonatal CHD is relatively higher in Jingzhou,and there are many risk factors.Comprehensive intervention should be conducted for the unfavorable factors during pregnancy.

关 键 词：先天性心脏病 新生儿 出生情况 影响因素 

分 类 号：R722.1[医药卫生—儿科]