生物催化法制备低聚半乳糖的研究进展  

Recent research progress on biocatalytic production of galactooligosaccharides

作　　者：何乃莹 竺胜权 黄金[1] HE Naiying;ZHU Shengquan;HUANG Jin(College of Pharmaceutical Science,Zhejiang University of Technology,Hangzhou 310014,China)

机构地区：[1]浙江工业大学药学院,浙江杭州310014

出　　处：《发酵科技通讯》2021年第1期20-27,共8页Bulletin of Fermentation Science and Technology

基　　金：天津市微生物代谢与发酵过程控制工程中心开放课题(ZXKF20180204)。

摘　　要：低聚半乳糖(Galactooligosaccharide,GOS)是一种倍受关注的功能性低聚糖益生元,能显著促进肠道益生菌的增殖,维持肠道菌群平衡,增强肌体免疫力。随着国内外研究的不断深入,GOS作为典型的非消化性低聚糖逐渐显示出其不可小觑的市场价值。笔者针对低聚半乳糖的理化性质、生理功效、用途、生物催化法制备机理、产物纯化及提取等方面的研究进展和工业化生产现状及其存在的问题进行了综述,并对低聚半乳糖产业未来发展前景进行了展望。Galactooligosaccharides(GOS)is a functional oligosaccharide that has attracted much attention in recent years.It is an outstanding prebiotic with merits of promoting the proliferation of beneficial intestinal bacteria,such as Bifidobacteria,maintaining the balance of intestinal flora,and enhancing the body immunity.Although the GOS has those advantages and overwhelming market value,studies on the GOS encounter several challenges.Focusing on the industrial manufacturing processes,this review summarizes the functions and applications of GOS,as well as biocatalytic synthesis methods and purification methods.Finally,we outlook the future development prospects of the galactooligosaccharide industrialization.

关 键 词：低聚半乳糖 Β-半乳糖苷酶 生物催化法制备 纯化 

分 类 号：TQ464.8[化学工程—制药化工]