中草药复方祛痘凝胶的研制及功效评价  

Development and evaluation of efficacy of Chinese herbal medicine compound anti-acne gel

作　　者：李奥丽 肖伟莉 王雪梅[1] 陈紫薇 孔小卫[2] LI Aoli;XIAO Weili;WANG Xuemei;CHEN Ziwei;KONG Xiaowei(College of Chemistry and Chemical Engineering, Anhui University, Hefei 230601, China;School of Life Sciences, Anhui University, Hefei 230601, China)

机构地区：[1]安徽大学化学化工学院,安徽合肥230601 [2]安徽大学生命科学学院,安徽合肥230601

出　　处：《安徽大学学报（自然科学版）》2021年第2期87-94,共8页Journal of Anhui University(Natural Science Edition)

基　　金：安徽省绿色高分子材料重点实验室资助项目(KF2012006)。

摘　　要：采用正交试验设计,通过对DPPH·自由基清除率、透明质酸酶抑制率、睾酮转化率以及对金黄色葡萄球菌抑菌作用的测试,优选出黄连、黄檗、黄芩、大黄水提液的最佳复配比,制备一款祛痘凝胶,并对该凝胶的感官和理化指标及功效进行测试,对试用者的祛痘效果进行跟踪研究和问卷调查,结果表明:该祛痘凝胶质地清爽、肤感舒适、无刺激,具有较好的祛痘功效.Through orthogonal experimental design,the best ratio of water extracts of Coptis chinensis,Cortex phellodendri,Radix scutellaria and Rheum officinale was optimized by testing of scavenging rates to DPPH,inhibition rate on hyaluronidase activity,testosterone conversion rate,and antibacterial effect on Staphylococcus aureus to prepare an anti-acne gels.Theirs sensory,physicochemical indicators and efficacy were tested,follow-up study and questionnaire was conducted on anti-acne effect of the trier.The results showed that the gel had a refreshing texture,comfortable skin feeling without irritation,and the better anti-acne effect.

关 键 词：正交试验 祛痘凝胶 四黄复配水提液 功效测试 

分 类 号：TQ630[化学工程—精细化工]