应激性心肌病与急性心肌梗死患者肌钙蛋白检查结果差异性  

Difference of troponin test results between patients with stress cardiomyopathy and acute myocardial infarction

作　　者：吴鹏程 王猛 张红兵 蒋崇慧[4] 黄澄[5] WU Pengcheng;WANG Meng;ZHANG Hongbing;JIANG Conghui;HUANG Cheng(Emergency Department,Zhongshan Torch Development Zone Hospital,Zhongshan,Guangdong,China,528437;Department of Cardiology,Zhongshan Torch Development Zone Hospital,Zhongshan,Guangdong,China,528437;Emergency Department,Nanlang Branch,Zhongshan People's Hospital,Zhongshan,Guangdong,China,528437;Department of Emergency,Zhongshan People's Hospital,Zhongshan,Guangdong,China,528437;Department of Cardiology,Guangdong Provincial People's Hospital,Guangdong,Guangzhou,China,510080)

机构地区：[1]中山火炬开发区医院急诊科,广东中山528437 [2]中山火炬开发区医院心内科,广东中山528437 [3]中山市人民医院南朗分院急诊科,广东中山528437 [4]中山市人民医院急诊科,广东中山528437 [5]广东省人民医院心内科,广东广州510080

出　　处：《分子诊断与治疗杂志》2021年第2期292-295,共4页Journal of Molecular Diagnostics and Therapy

摘　　要：目的分析应激性心肌病与急性心肌梗死患者肌钙蛋白检查结果差异性。方法收集分析本院2018年1月至2020年6月收治的10例应激性心肌病患者(应激性心肌病组)以及100例急性心肌梗死患者(急性心肌梗死组)临床资料,对两组患者肌钙蛋白(肌钙蛋白T、肌钙蛋白I)、心肌酶谱(ALT、AST、CK、CK-MB、LDH)、心电图表现(I导联抬高、aVL导联抬高、V2-V5导联ST段抬高)进行对比,利用Spreaman相关性分析法检验以上指标与应激性心肌病的相关性,绘制受试者工作特征曲线计算应激性心肌病与急性心肌梗死肌钙蛋白的cut-off值。结果两组患者肌钙蛋白检测结果比较,应激性心肌病组CTNT及CTNI值分别为(0.46±0.05)μg/L,(3.67±0.41)μg/L,高于急性心肌梗死组的(1.27±0.11)μg/L,(24.38±1.42)μg/L,差异有统计学意义(P<0.05),心肌酶谱检测结果、心电图表现相比较,差异无统计学意义(P>0.05);Spreaman相关性分析结果显示,肌钙蛋白与应激性心肌病有关,心肌酶谱、心电图表现与与应激性心肌病无关;受试者工作特征曲线显示:应激性心肌病与急性心肌梗死肌钙蛋白T的cut-off值为0.97μg/L、肌钙蛋白I的cut-off值为7.71μg/L。结论肌钙蛋白检查结果可以作为应激性心肌病、急性心肌病梗死的初步诊断。Objective To analyze the difference of troponin test results between patients with stress cardiomyopathy and acute myocardial infarction.Methods The clinical data of 10 patients with stress cardiomyopathy(stress cardiomyopathy group)and 100 patients with acute myocardial infarction(acute myo⁃cardial infarction group)admitted to our hospital from January 2018 to June 2020 were collected and analyzed.Group of patients with troponin(troponin T,troponin I),myocardial enzyme spectrum(ALT,AST,CK,CK⁃MB,LDH),electrocardiogram(lead I elevation,aVL lead elevation,V2⁃V5 lead ST segment elevation)for comparison,Spreaman correlation analysis method was used to test the correlation between the above indicators and stress cardiomyopathy,and the receiver operating characteristic curve was drawn to calculate the muscle calcium of stress cardiomyopathy and acute myocardial infarction The cut⁃off value of the protein.Results Comparing the results of troponin detection between the two groups,the values of CTNT and CTNI in the stress cardiomyopathy group were(0.46±0.05)μg/L and(3.67±0.41)μg/L,respectively,which were higher than those in the acute myocardial infarction group(1.27±0.11)μg/L,(24.38±1.42)μg/L,the differ⁃ence was statistically significant(P<0.05),compared with the results of myocardial enzyme spectrum and elec⁃trocardiogram,the difference was not statistically significant(P>0.05);Spreaman Correlation analysis results suggest that troponin is related to stress cardiomyopathy,and myocardial enzyme spectrum and electrocardio⁃gram have nothing to do with stress cardiomyopathy;receiver operating characteristic curve suggests:stress cardiomyopathy and acute myocardial infarction muscle The cut⁃off value of calcineurin T was 0.97μg/L,and the cut⁃off value of troponin I was 7.71μg/L.Conclusion The results of troponin examination can be used as a preliminary diagnosis of stress cardiomyopathy and acute cardiomyopathy infarction.

关 键 词：应激性心肌病 急性心肌梗死 肌钙蛋白 心肌酶谱 

分 类 号：R542.22[医药卫生—心血管疾病]